摘要
石蠟瘤是一種因外來礦物油造成的特殊外來物反應，我們在此報告一例涵蓋身體皮膚
多處的廣泛性的石蠟瘤個案。一位三十四歲男性來診發現在胸部、上臂、殿部、及下肢多
處有許多黃褐色的硬塊，詢問病蚔發現病患曾自我施打嬰兒油等液狀的油性物質於這些病
灶處，總量大於兩公升。組織病理檢查發現在真皮及皮下脂肪處有許多大小不等的空洞，
間質並有明顯纖維化一此特徵類似瑞士起士。以oil red O染色發現這些空洞內含脂質。廣
泛性的石蠟油瘤是一罕見的病例。據我們所知，在台灣從未報導過，我們將三個病人主訴
有疼痛感的結節型硬塊全切除，追蹤三個月以上並無復發。(中華皮誌21:268-274, 2003)
關鍵字
無資料並列摘要
Paraffinoma (sclerosing lipogranuloma) is a distinct foreign body reaction caused by the intro-
duction of mineral oils. Widespread paraffinoma is rare and, to our knowledge, has never been report-
ed in Taiwan. We herein report a 34-year-old man with widespread self-inflicted paraffinomas
involving multiple anatomic sites. The patient had self-injected vast amount of bady oil and other oily
substances (more than two liters) into these lesions in an apparent attempt to cure his muscle inflam-
mation. Histopathologically, multiple empty cysts were seen in the sclerotic dermis and subcutis with
the characteristic “Swiss-cheese” appearance; oil red O stain demonstrated the presence of lipids
within the cysts. We excised three painful nodular lesions and no recurrences were noted after more
than three months of follow up. (Dermatol sinica 20:268-274, 2003)
延伸閱讀
- Wu, M. F., Huang, T. W., Chang, H., & Lee, S. C. (2016). 罕見之廣泛性惡性間皮瘤. 胸腔醫學, 31(4), 256-260. https://www.airitilibrary.com/Article/Detail?DocID=10239855-201608-201607270011-201607270011-256-260
- 顧哲銘、朱敬中、賴義雄（2001）。會厭軟骨之惡性纖維組織細胞瘤併鱗狀上皮細胞癌 — 病例報告。中華民國耳鼻喉科醫學雜誌，36(3)，177-180。https://doi.org/10.6286/2001.36.3.177
- 吳庭輝、陳啟信、吳景義、王榮德、李俊賢（2009）。職業石綿暴露引起之惡性間皮瘤病例報告。台灣醫學，13(5)，461-470。https://doi.org/10.6320/FJM.2009.13(5).04
- 莊弘毅、李俊賢、陳怡君（2009）。惡性間皮瘤與石綿暴露個案討論及職業相關探討。環境職業醫學會訊，(9804)，13-21。https://doi.org/10.6670/EOMA.2009.16(4).13-21
- 羅書宜、黃展慶、王肇齡、莊弘毅、何啓功（2022）。石綿暴露造成腹膜惡性間皮細胞瘤之個案報告。中華職業醫學雜誌，29(2)，111-120。https://www.airitilibrary.com/Article/Detail?DocID=10233660-202204-202205050009-202205050009-111-120