This study examines the issues of race that are explored in the movies of director Spike Lee, focusing on the various different ways in which black people in the American experience alienation. The concept of post-colonialism, as developed by Frantz Fanon, is used as the study's analytical framework, making use of post-colonialism's existentialism and dialectics to explore the behavior that black Americans display due to the influence of colonialism. The study begins by describing the subjects' conscious behavior, and then uses this as a basis for explaining the colonial alienation and labor alienation experienced by black people in America, before going on to consider alienation as experienced by Spike Lee himself. The study finds that Spike Lee became aware at an early age of his own alienated self, and that his efforts to use his movies to help viewers achieve de-alienation have also helped Lee himself to achieve a similar de-alienation.