The purpose of this paper is to assess Netbook's application on e-book readings. The study is based on the literature reviews and on-site interview with representative from Asus, which is the leading Netbook production enterprise. The results of this study indicate that: 1.Netbook will become the mainstream product in the future computer market. 2.E-reader, with no doubt, would have a promising outlook. 3.Netbook, which provides more functions than e-reader, will provide more options to customers. 4.There are many e-book applications of Netbook that are capable to compete with those dedicate e-readers.