Purposes: To understand the factors related to Taiwanese people's confidence levels in TV food safety information and online food safety information. Methods: A total of 1,751 subjects were studied by a secondary data analysis with the cross-sectional research method using data from ＂The 2016 Taiwan Communication Survey (Phase One, Year Five): Risk and Disaster Communication.＂ The dependent variables of the data analysis were (1) whether they believed in TV food safety information, and (2) whether they believed in online food safety information. The questionnaire's independent variables included basic data, namely, gender, age, education level, information sharing behavior, the effectiveness of the government, individual's number of medical care visits, perception of food safety incidents, and personal values. From the descriptive analysis, Chi-square test, t-test, and logistic regression, the related factors were obtained. Results: The confidence in TV food safety information (83.8%) was higher than online food safety information (69.7%). The logistic regression analysis revealed that believing in TV food safety information significantly correlated with females, groups with information-sharing behavior, believing in government effectiveness, perception of food safety incidents, and the self-interest aspect of personal values. Believing in online food safety information significantly correlated with females, the 18-69 age group, education level, groups with information-sharing behavior, believing in government effectiveness, and the self-interest aspect of personal values. Conclusions: Various factors significantly influenced people's confidence level in TV food safety information and online food safety information. The research results can serve as a basis for planning food safety prevention and intervention strategies in Taiwan.