動物園野生貓科動物之似貓免疫不全病毒感染情形

Incidence of Feline Immunodeficiency Virus-like Lentivirus Infection in Exotic Felids in Taipei City Zoo

嚴慧玲(Hui-Lin Yen) ； 闕玲玲(Ling-Ling Chueh) ； 季昭華(Chao-Hwa Chi) ； 周健(Jiann Jou) ； 龐飛(Victor Fei Pang) ； 鄭謙仁(Chian-Ren Jeng)

《中華民國獸醫學會雜誌》 25卷2期 (1999/06) Pp. 113-118

https://doi.org/10.7009/JTCSVS.199906.0113

摘要

利用酵素連接吸附法（ELISA）、間接螢光染色法（IFA）及西方墨點法，檢測台北市立動物園血清庫中9種野生貓科動物的44個血清樣材，是否含有與家貓兔疫不全病毒（Feline immunodeficiency virus；FIV）反應的抗體存在，測試動物種別包括老虎、獅子、雲豹、林曳、山獅、截尾貓、石虎、花豹及豹貓。在受檢樣材中有3個獅子血清與FIV產生交叉陽性反應。經進一步調查，此3個陽性血清係來自一隻母獅及其生育之兩隻獅子，但三者自前並無任何臨床症狀。在三種檢測法中ELISA的檢測結果和西方墨點法大致一樣。自檢驗結果顯示，動物園中野生貓科動物已存在似貓免疫不全病毒之陽性感染族群；為防其擴散，宜對此疾病作例行篩撿，並由其結果調整其飼養管理。

關鍵字

貓免疫不全病毒 ； 似貓免疫不全病毒之慢病毒 ； 野生貓科動物

並列摘要

This study is concerned with the prevalence of feline immunodeficiency virus-like lentivirus (FIV-like lentivirus) infection in Taipei City Zoo. Forty four serum samples from nine wild felids, including a Bengal tiger (Panthera tigris), African lion (Panthera leo), clouded leopard (Neofelis nebulosa), Iynx (Lynx Iynx), puma (Felis concolor), bobcat (Lynx rufus), Chinese leopard cat (Felis p. bengalensis), leopard (Panthera pardus), and ocelot (Leopardus pardalis), were evaluated for antibodies against antigen derived from a domestic cat FIV by a commercial ELISA kit, immunofluorescence assay, and western blot. Antibodies to FIV were detected from three African lions that included a lioness and its two offspring. No clinical signs were observed in these infected animals. Results obtained from the commercial ELISA kit corresponded to those of the western blot, suggesting that the commercial kit is suitable for early screening of the FIV-like lentivirus infection in wild felids. This survey provides evidence of an FIV-like lentivirus infection in the lion species in Taipei City Zoo. Routine monitoring of the FIV-like lentivirus may be necessary for the management and movement of wild felids in the zoo.

並列關鍵字

Feline immunodeficiency virus ； FIV-like lentivirus ； Wild felids