- 期刊
全靜脈營養輸注院內感染之影響因素探討
The Prospective Study for the Effect Factors of Nosocomial Infection with Total Parenteral Nutrition Infusate
摘要
The aims of this study were to display the incidences of infections and risk factors of total parenteral nutrition (TPN) via central venous catheter. The objects included all the patients aged 15 and Over who had TPN infusion in a medical center. In the prospective study, there were 1,134 patients having accept TPN infusate with in three years. The crude infection rate was 11.5%, including 9.3% bloodstream infection, 2.2% inject site infection, and 1.1% catheter-related blood-stream infection. The incidence density of infection was 5.4 episodes. The mean age of all patients who accepted TPN infusate were 64.4±16.1. The age of infection and no infection had significant statistic difference (p＜0.05). Further stratified analysis showed the risk that 76 and older infection was 2.39 times (95% CI 1.14-5.14, p＜0.05) higher than 45 and younger. The infection of the TPN infusate of 21-30 days and 31 days above were higher than 1-lOdays by 4.96 times and 8.07 times (p＜0.00 1) respectively. All potential risk factors by logistic regression analysis founded the TPN infusate over 21 days for these over 76 years to have significant statistics difference (p＜O.05) too. Conclusion: over 76 year olds and over 21-day TPN infusate are risky factors of nosocomial infection.
並列摘要
The aims of this study were to display the incidences of infections and risk factors of total parenteral nutrition (TPN) via central venous catheter. The objects included all the patients aged 15 and Over who had TPN infusion in a medical center. In the prospective study, there were 1,134 patients having accept TPN infusate with in three years. The crude infection rate was 11.5%, including 9.3% bloodstream infection, 2.2% inject site infection, and 1.1% catheter-related blood-stream infection. The incidence density of infection was 5.4 episodes. The mean age of all patients who accepted TPN infusate were 64.4±16.1. The age of infection and no infection had significant statistic difference (p＜0.05). Further stratified analysis showed the risk that 76 and older infection was 2.39 times (95% CI 1.14-5.14, p＜0.05) higher than 45 and younger. The infection of the TPN infusate of 21-30 days and 31 days above were higher than 1-lOdays by 4.96 times and 8.07 times (p＜0.00 1) respectively. All potential risk factors by logistic regression analysis founded the TPN infusate over 21 days for these over 76 years to have significant statistics difference (p＜O.05) too. Conclusion: over 76 year olds and over 21-day TPN infusate are risky factors of nosocomial infection.
延伸閱讀
- 李凰瓊、鄭立勤、周來香、蘇秀真、陳慧娟、楊俊杰（2015）。接受全靜脈營養的成人病患發生中心靜脈導管感染的相關危險因子。臺灣營養學會雜誌，39(3)，88-94。https://doi.org/10.6691/NSJ.201501_39(3).0003
- 王曉婷、徐明儀、廖浚凱（2020）。血液腫瘤病人中心靜脈導管血流感染相關因素之探討。腫瘤護理雜誌，20(1)，5-18。https://doi.org/10.6880/TJON.202006_20(1).01
- 宋佳穎（2005）。某醫學中心外科加護病房使用中心靜脈導管引起院內感染之相關因素探討〔碩士論文，中山醫學大學〕。華藝線上圖書館。https://doi.org/10.6834/CSMU.2005.00066
- Chang, J. M., Chen, H. C., Tsai, J. C., Hwang, S. J., Guh, J. Y., & Lai, Y. H. (2000). Effect of Amino-acid Based Peritoneal Dialysate (Nutrineal®) on the Biochemical Nutritional Indices in CAPD Patients. Acta Nephrologica, 14(4), 327-327. https://www.airitilibrary.com/Article/Detail?DocID=10131671-200010-14-4-327-327-o
- 連淑華、魏秀義、江建勳、林嘉伯（2000）。The Quality Investigation of Large Volume Parenteral (Glucose Injection Solution) with Pyrogen Testing。藥物食品檢驗局調查研究年報，()，33-40。https://doi.org/10.6946/ASRNL.200009.0033