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Recycled Palm Oil Is Better than Soy Oil in Maintaining Bone Properties in a Menopausal Syndrome Model of Ovariectomized Rat

回鍋棕櫚油在維持有更年期症狀卵巢切除的大鼠之骨質狀況較黃豆油佳

摘要


棕櫚油具抗氧化作用、抗癌及降低膽固醇之效力。它比起其他如黃豆油等炸油,在加熱時抗氧化作用。當炸油重複地加熱,會生成毒性降解產物像是醛類,在被攝取後可能被吸收進入系統循環中。我們研究卵巢切除的大鼠攝取混合黃豆油或是棕櫚油的大鼠飼料,對骨質組織型態學參數之影響。將母的Sprague-Dawley大鼠分成八組:(1)正常控制組;(2)卵巢切除控制組;(3)卵巢切除及新鮮黃豆油;(4)卵巢切除及加熱一次黃豆油;(5)卵巢切除及加熱五次黃豆油;(6)卵巢切除及新鮮棕櫚油;(7)卵巢切除及加熱一次棕櫚油;(8)卵巢切除及加熱五次棕櫚油。這些油脂與大鼠飼料以大鼠體重比為15:100的比例混合,每天給予此食物共六個月。卵巢切除對骨質組織型態學參數有負面影響。攝取新鮮及加熱一次的油可以提供保護作用,對抗卵巢切除術的負面影響,但是這些保護作用在加熱五次的油則消失。大豆油加熱五次確實使卵巢切除大鼠的組織型態學參數變得較差。因此,對於有骨質疏鬆危險性的已停經者而言,最好使用棕櫚油當做炸油,尤其是習慣使用回鍋油者。

並列摘要


Palm oil is shown to have antioxidant, anticancer and cholesterol lowering effects. It is resistant to oxidation when heated compared to other frying oils such as soy oil. When a frying oil is heated repeatedly, it forms toxic degradation products, such as aldehydes which when consumed, may be absorbed into the systemic circulation. We have studied the effects of taking soy or palm oil that were mixed with rat chow on the bone histomorphometric parameters of ovariectomised rats. Female Sprague-Dawley rats were divided into eight groups: (1) normal control group; (2) ovariectomised-control group; (3) ovariectomised and fresh soy oil; (4) ovariectomised and soy oil heated once; (5) ovariectomised and soy oil heated five times; (6) ovariectomised and fresh palm oil; (7) ovariectomised and palm oil heated once; (8) ovariectomised and palm oil heated five times. These oils were mixed with rat chow at weight ratio of 15:100 and were given to the rats daily for six months. Ovariectomy had caused negative effects on the bone histomorphometric parameters. Ingestion of both fresh and onceheated oils, were able to offer protections against the negative effects of ovariectomy, but these protections were lost when the oils were heated five times. Soy oil that was heated five times actually worsens the histomorphometric parameters of ovariectomised rats. Therefore, it may be better for postmenopausal who are at risk of osteoporosis to use palm oil as frying oil especially if they practice recycling of frying oils.

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