Nuts, Inflammation and Insulin Resistance

核果類與發炎作用及胰島素抗性

Patricia Casas-Agustench ； Mònica Bulló ； Jordi Salas-Salvadó

《Asia Pacific Journal of Clinical Nutrition》 19卷1期 (2010/03) Pp. 124-130

https://doi.org/10.6133/apjcn.2010.19.1.17

摘要

食用核果類對於心血管疾病的益處已被廣泛的證實。這些保護的效應主要歸因於核果類在脂質和脂蛋白代謝上所扮演的角色。慢性發炎是動脈粥狀硬化進程的早期關鍵階段，將預測未來心血管疾病的發生，並且與胰島素抗性的致病密切相關，因此很多近期的研究專注於核果類的食用對於發炎及胰島素抗性的影響。經由不同的機制，一些核果類的成分，例如鎂、纖維、α-亞麻油酸、L-精胺酸、抗氧化物及單元不飽和脂肪酸，可能對於發炎及胰島素抗性有保護的作用。本文回顧人類流行病學的研究及人體實驗的證據來論證核果類的攝取與此兩種新興的心血管保護機制之間的關係。

關鍵字

核果類 ； 發炎 ； 胰島素抗性 ； 第II型糖尿病 ； 心血管疾病

並列摘要

The beneficial effects of nut consumption on cardiovascular disease (CVD) have been widely documented. These protective effects are mainly attributed to the role of nuts in the metabolism of lipids and lipoproteins. As chronic inflammation is a key early stage in the atherosclerotic process that predicts future CVD events and is closely related to the pathogenesis of insulin resistance, many recent studies have focused on the potential effect of nut consumption on inflammation and insulin resistance. Through different mechanisms, some components of nuts such as magnesium, fiber, α-linolenic acid, L-arginine, antioxidants and MUFA may protect against inflammation and insulin resistance. This review evaluates the epidemiologic and experimental evidence in humans demonstrating an association between nut consumption and these two emergent cardio-protective mechanisms.

並列關鍵字

nuts ； inflammation ； insulin resistance ； type 2 diabetes ； cardiovascular disease