Higher Cadmium Burden in Coastal Areas than in Inland Areas in Korea: Implications for Seafood Intake

此调查旨在研究韩国沿海人群和内陆人群体内镉（Cd）含量的差别。此项调查共有268位不吸烟的健康中年女性参加（年龄30-49岁，其中有88位来自8个沿海区域，180位来自15个内陆区域）。对她们采集外周血样和随机尿样，从而了解血液镉（Cd-B）和尿液镉（Cd-U）的含量。采用石墨炉原子吸收分光光度法测定Cd-B和Cd-U。结果显示，内陆和沿海居民Cd含量的几何平均值Cd-B分别为1.7 μg/L和1.72 μg/L；Cd-U（Cd-Uob）分别为1.54 μg/L和1.00 μg/L；肌酐矫正值（Cd-Ucr）为2.59 μg/g肌酐和1.81 μg/g肌酐。沿海居民Cd-Uob和Cd-Ucr均高于内陆居民，其原因可能是沿海居民生活接触大量镉有关。值得注意的是，沿海地区鱼类和贝类的摄入可能是其体内Cd的主要来源。本研究表明，韩国沿海地区居民镉负担要高于内陆居民。

關鍵字

血液；尿液；镉；沿海地区；暴露标志物

並列摘要

This survey was initiated to examine possible coastal-inland differences in cadmium (Cd) burden in general Korean populations. In total, 268 healthy non-smoking middle-aged women (30 to 49 years; 88 residents in 8 coastal areas and 180 residents in 15 inland areas) participated in the study. They offered peripheral blood and spot urine samples so that cadmium in blood (Cd-B) and urine (Cd-U) were taken as exposure markers. Determination of Cd-B and Cd-U was carried out by graphite furnace atomic absorption spectrophotometry. With regard to Cd burden, geometric means for the coastal and inland residents were 1.70 and 1.72 μg/L for Cd-B, 1.54 and 1.00 μg/L for Cd-U as observed (Cd-U), 2.59 and 1.81 μg/g creatinine for Cd-U as corrected for creatinine (Cd-U_(cr)), respectively. Cd-U and Cd-U_(cr) were higher in the coastal areas than in inland areas. Reasons for higher Cd-U in the coastal areas than in the inland areas were are discussed in relation to major sources of Cd in daily life of the residents. Attention was paid to consumption of fish and shellfish in the coastal areas as major sources of dietary Cd intake. This study shows that Cd burdens were higher in coastal areas than in inland areas in Korea.

並列關鍵字

blood ； urine ； cadmium ； coastal areas ； exposure marker

參考文獻

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國際替代計量

Higher Cadmium Burden in Coastal Areas than in Inland Areas in Korea: Implications for Seafood Intake

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