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Dedifferentiated Liposarcoma of Mesentery with High-Grade Osteosarcomatous Differentiation: Report of a Case

腸繫膜的去分化脂肪瘤具罕見的骨瘤分化:病例報告

摘要


一名32歲成年男性因急性腹痛求診。腹部電腦斷層發現一個巨大的腹部腫瘤,其組成主要是實心的脂肪成分並部分空腔形成,在某些區域可看到鈣化或骨化,組織學檢查發現腫瘤的主要成分爲分化良好的脂肪肉瘤及高惡性度的脂肪肉瘤,合併可以看到某些異性分化的區域,包括惡性纖維組織球瘤、骨瘤及軟骨瘤的分化,診斷爲去分化脂肪肉瘤:手術切除後,病人每半年接受腹部電腦斷層及胸部影像檢查,至今一年沒有發現復發或轉移。去分化脂肪瘤具骨瘤分化是個罕見的病例,目前英文文獻上只有9例;因在腹部的去分化脂肪瘤具有較高的復發率,故定期追蹤治療是必要的。

關鍵字

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並列摘要


Dedifferentiated liposarcoma occurs in up to 10% of cases of well differentiated liposarcoma with non-lipogenic sarcoma components. Among the heterologus components, osteosarcoma is very rare. We report a 32 year-old man presenting with sudden onset of abdominal pain. Computed tomography revealed a huge intraabdominal mass with solid/cystic and fat components as well as areas of calcification/ossification. Histological examination showed well differentiated liposarcoma, high-grade liposarcoma with areas of heterologus differentiation, including malignant fibrous histiocytoma (MFH)-like, chondrosarcomatous and osteosarcomatous components. Dedifferentiated liposarcoma was diagnosed. After operation, the patient has been regularly followed up every half a year. No recurrence has hither to been noted for one year.

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