Falls and Atrial Fibrillation in Elderly Patients

Chen-Ying Hung ； Tsu-Juey Wu ； Kuo-Yang Wang ； Jin-Long Huang ； El-Wui Loh ； Yi-Ming Chen ； Chu-Sheng Lin ； Ching-Heng Lin ； Der-Yuan Chen ； Yih-Jing Tang

《Acta Cardiologica Sinica》 29卷5期 (2013/09) Pp. 436-443

並列摘要

Background: Atrial fibrillation is a common heart rhythm disorder in older adults, and its prevalence has increased rapidly in recent years. The health issues associated with atrial fibrillation are not limited to physiological problems，as it also contributes to an increased risk of falls, which may be related to cardiovascular co-morbidities and medication use. The aim of this study was to determine which cardiovascular co-morbidities and medication use are associated with falls in older adults with atrial fibrillation.Methods: Four hundred and one patients 75 years of age or older (82.2 ± 0.2 years) were enrolled in a geriatric evaluation and management unit in Taiwan. Events associated with patient falls and medication use were recorded, and comprehensive geriatric assessment was conducted during admission.Results: Among the study participants, 66 (16.5%) patients had atrial fibrillation and 234 (58.4%) patients had a history of fall. We found a significantly higher prevalence of falls in patients with atrial fibrillation [odds ration (OR) 1.98, 95% confidence interval (CI) 1.08-3.63, P = 0.026] compared with those without atrial fibrillation. Using multivariate logistic regression, we found that benzodiazepine use (OR 18.22, 95% CI 2.71-122.38, P = 0.003), a history of paroxysmal atrial fibrillation (OR 12.18, 95% CI 1.37-108.70, P = 0.025) and hypertension (OR 9.49, 95% CI 1.19-75.57, P = 0.034) were independent factors for falls in atrial fibrillation patients.Conclusions: A diagnosis of atrial fibrillation in elderly patients is associated with falls. Benzodiazepine use, history of paroxysmal atrial fibrillation, and hypertension were associated with a high falling prevalence among patients with atrial fibrillation.

並列關鍵字

Atrial fibrillation ； Benzodiazepine ； Falls ； Hypertension