The use of antibiotic-impregnated acrylic cement as bone spacer between the interval of revision hip arthroplasty for infection has been widely described and practiced. The devastating complications of cement spacer were also noted more frequently. A 67-year-old woman presented with tense swelling over left lower limb and hemarthroses of left hip after implantation of a cement spacer for infected hip arthroplasty. Complete external compression of the iliac vein and laceration of the iliac artery by the spacer were found. Removal of the spacer and femoral stem, surgical debridement and repair of the vessel were performed. There was no clinical sign of infection at the latest follow-up of one year.