The Presence of Dental Disorders Correlated with Increasing Helicobacter Pylori Prevalence in Adolescents and Young Adults

牙齒疾病與幽門桿菌在青少年和年輕成年人成長階段陽性率上升有關

鄭修琦(Hsiu-Chi Cheng) ； 楊燿榮(Yao-Jong Yang) ； 許博翔(Bor-Shyang Sheu) ； 張維倫(Wei-Lun Chang) ； 楊曉白(Hsiao-Bai Yang) ； 趙文慶(Wen-Shin Chao)

《臺灣消化醫學雜誌》 26卷2期 (2009/06) Pp. 140-147

https://doi.org/10.6557/GJT.200906_26(2).0001

摘要

Background and aims: The oral cavity has been observed as an alternative niche to harbor H. pylori. We hypothesized the presence of dental disorders could be related to the increasing H. pylori prevalence in adolescences and young adults.
Methods: A total of 611 students (201 from a junior-high school, 204 from a senior-high school, and 206 from a university) were enrolled to assess presence of anti-H. pylori immunoglobulin G and underwent formal dental assessment by trained personnel.
Results: H. pylori seropositivity increased with the chronological age of students in junior high school, in senior high school and in university (17.9%, 29.9%, and 38.8%, P＜0.001), respectively. Moreover, the rates of dental disorders increased in the same order (34.3%, 41.7%, and 50.5%, P=0.004). The overall H. pylori seropositivity was higher in students with dental disorders (132 [51.2%] of 258) than in those without (45 [10.4%] of 433) (P＜0.001). The seroprevalence rates of H. pylori significantly increased by chronological age in those students with dental disorders in junior high school, high school and university (34.8%, 52.9%, and 60.6%, P=0.002). Multiple logistic regression analysis confirmed that the presence of dental disorder is an independent risk factor to having positive H. pylori seropositivity among teenagers (P＜0.001).
Conclusion: The presence of dental disorder could be a risk factor for increased prevalence of H. pylori seropositivity in adolescents and young adults. Dental care could be a promising avenue to prevent H. pylori infection in adolescents and young adults.

關鍵字

幽門桿菌 ； 抗體 ； 牙齒疾病 ； 青少年

並列摘要

Background and aims: The oral cavity has been observed as an alternative niche to harbor H. pylori. We hypothesized the presence of dental disorders could be related to the increasing H. pylori prevalence in adolescences and young adults.
Methods: A total of 611 students (201 from a junior-high school, 204 from a senior-high school, and 206 from a university) were enrolled to assess presence of anti-H. pylori immunoglobulin G and underwent formal dental assessment by trained personnel.
Results: H. pylori seropositivity increased with the chronological age of students in junior high school, in senior high school and in university (17.9%, 29.9%, and 38.8%, P＜0.001), respectively. Moreover, the rates of dental disorders increased in the same order (34.3%, 41.7%, and 50.5%, P=0.004). The overall H. pylori seropositivity was higher in students with dental disorders (132 [51.2%] of 258) than in those without (45 [10.4%] of 433) (P＜0.001). The seroprevalence rates of H. pylori significantly increased by chronological age in those students with dental disorders in junior high school, high school and university (34.8%, 52.9%, and 60.6%, P=0.002). Multiple logistic regression analysis confirmed that the presence of dental disorder is an independent risk factor to having positive H. pylori seropositivity among teenagers (P＜0.001).
Conclusion: The presence of dental disorder could be a risk factor for increased prevalence of H. pylori seropositivity in adolescents and young adults. Dental care could be a promising avenue to prevent H. pylori infection in adolescents and young adults.

並列關鍵字

H. pylori ； IgG ； dental diseases ； adolescents