Breast cancer is still one of the major causes of cancer deaths for women in Taiwan. To assess the validity of mammographic needle localization in detecting clinically occult breast tumors, we performed needle localization procedures on 46 cases, and the mean age of the patients was 37 years. The mammographic findings included microcalcifications and/or mass density. The localized lesion was most frequently microcalcification (76.1%) and least frequently mass density with microcalcifications (10.9%). The most common pathological findings for benign lesions was fibrocystic change (78.4%) and intraductal carcinoma (88.9%) for malignant tumors. There was also one case of ductal carcinoma in situ (11.1%). Overall, the incidence of positive biopsies for cancer was 19.6%, which was similar to that in other countries. We conclude that the needle localization is a valid procedure for localizing non-palpable occult breast lesions.