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摘要


血管肉瘤是一種高度惡性且預後極差的血管腫瘤。這種腫瘤大部分發生在頭頸部的皮膚或表淺的軟組織,僅有少數發生在臟器。在本文中我們的目的是針對罹患血管肉瘤病患之臨床資料及影像學的表現加以分析,並且比較臟器型及非臟器型血管肉瘤之不同。此外,我們也針對血管肉瘤與血管外皮細胞之不同加以分析。本研究包括十四年來經過病理診斷為血管肉瘤之十四位病患,其中男性及女性病患各有七位,而平均年齡為五十三歲。所有的臨床資料及影像學檢查均加以回顧,其中包括十個電腦斷層檢查及兩個磁振造影檢查。我們並將本研究所有血管內瘤的臨床資料與我們以前所報告的血管外皮細胞瘤的臨床資料加以比較。臟器型血管肉瘤與非臟器型血管肉瘤各佔全部的百分之五十。臟器型血管肉瘤的腫塊大小及遠處轉移的機率也比非臟器型血管肉瘤來的大。此外,臟器型血管肉瘤的兩年及五年存活率都比非臟器型血管肉瘤來的低。臟器型及非臟器血管肉瘤之平均存活時間各別為43.6個月與17.7個月。大部分腫瘤在顯影劑顯影之電腦斷層上呈現出不規則的邊緣、不均勻且不同程度、不同型態的顯影。而血管肉瘤與血管外皮細胞瘤的兩年存活率各為43%及61%。在本研究中,臟器型血管肉瘤比非臟器型血管肉瘤更為常見且預後更差。血管外皮細胞瘤的預後比非臟器型血管肉瘤低但比臟器型血管肉瘤來的高。影像學的特徵並不具專一性但符合高血管性腫瘤的特徵。

並列摘要


Angiosarcomas are highly malignant neoplasms of vascular origin. They most commonly arise from the skin and subcutaneous soft tissue of the head and neck, with only a small percentage of tumors from the viscera. In this article, we evaluated the clinical and imaging features of angiosarcomas and compared visceral angiosarcomas with nonvisceral angiosarcomas. A comparison between angiosarcomas and hemangiopericytomas was performed as well. This study included 14 patients (7 men, 7 women, averaging 53 years) with pathologically confirmed angiosarcomas during a period of 14 years. All clinical data and images, including computed tomography (CT) images in 10 patients and magnetic resonance images (MRI) in two, were reviewed. The clinical data of angiosarcomas in the present study were also compared with those of hemangiopericytomas from our previously reported study. Visceral and nonvisceral each comprised 50% of all angiosarcomas in the study. Visceral angiosarcomas were larger at the time of diagnosis than nonvisceral angiosceral angiosarcomas. The metastatic rate was much higher for patients with visceral angiosarcomas than for those with nonvisceral angiosarcomas. The overall 2-year and 5-year survival rates were lower for patients with visceral angiosarcomas than for those with nonvisceral angiosarcomas. Most lesions were ill defined, heterogeneous, and had variable degrees and patterns of enhancement on contrast-enhanced CT images. The overall two-year survival rate for the patients with angiosarcomas and those with previously reported hemangiopericytomas were 43% and 61% respectively. Angiosarcomas were heterogeneously hypointense on T1-weighted MR images and hyperintense on T2-weighted MR images. In our report, visceral angiosarcomas were more common, had higher metastatic rates, and poorer prognosis than nonvisceral angiosarcomas. Imaging features were nonspecific to angiosarcomas but were characteristic for hypervascular tumors. The prognosis for patients with hemangiopericytomas was poorer than for those with nonvisceral angiosarcomas, but better than for those with visceral angiosarcomas.

並列關鍵字

Angiosarcoma CT MR

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