Life-Threatening Interstitial Pneumonitis Induced by a Chinese Herbal Medicine, Fang Feng Tong San (Bofu-tsusho-san), Used for Intentional Weight Loss: A Case Report

使用中藥“防風通聖散”減肥而引起危及生命之間質性肺炎－病例報告

唐士恩(Shih-En Tang) ； 簡志峰(Chih-Feng Chian) ； 吳清平(Chin-Pyng Wu) ； 彭萬誠(Wann-Cherng Perng)

《胸腔醫學》 22卷6期 (2007/12) Pp. 448-454

https://doi.org/10.29806/TM.200712.0012

摘要

有越來越多的藥物被知道會造成不同疾病程度的間質性肺炎，可能從輕微的肺部浸潤至嚴重危及生命的急性呼吸衰竭。目前有許多中藥造成間質性肺炎的病例被報導，我們報告一位病人呈現漸進性呼吸困難及發燒並導致呼吸衰竭，胸部X光片呈現廣泛肺浸潤，經影像輔助胸腔鏡手術(VATS)肺切片顯示為間質性肺炎，經詳細詢問病史，病人承認在入院前十天開始使用中藥防風通聖散作為減肥目的使用，病人在接受類固醇治療後臨床症狀明顯改善。對於難以解釋的間質性肺炎，醫師應將藥物造成間質性肺炎納入考量，包括中藥。

關鍵字

防風通聖散 ； 間質性肺炎 ； 中藥 ； 減肥藥

並列摘要

An increasing number of drugs can induce distinctive patterns of interstitial lung disease, ranging from benign infiltrates to life-threatening acute respiratory failure. We report a patient who presented with progressive dyspnea and fever that were complicated by acute respiratory failure. The chest roentgenograph revealed a diffuse ground-glass pattern; interstitial pneumonitis was diagnosed after video-assisted thoracoscopic lung biopsy. The patient admitted using the Chinese herbal medicine Fang Feng Tong San (Bofu-tsusho-san in Japanese) for intentional weight loss for about 10 days before admission. Her condition improved after treatment with corticosteroid. Drug-induced interstitial lung disease, including that caused by herbal medicines, should be considered in any patient with unexplained interstitial pneumonitis.

並列關鍵字

Fang Feng Tong San ； Bofu-tsusho-san ； interstitial pneumonitis ； Chinese herbal medicine ； weight loss