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Primary Malignant Fibrous Histiocytoma of the Lung with an Initial Presentation of Extremities Pain: A Case Report

原發性肺部惡性纖維組織瘤以雙下肢疼痛爲表現:病例報告

摘要


原發性肺部惡性纖維組織瘤為一類極罕見之肺癌。診斷為肺原發前必須先排除其他原發部位。必須檢查病人是否有轉移病灶。預後因素決定在手術切除範圍,目前沒有證據証明術後化學療法和放射療法之好處。本病例是首位以雙下肢疼痛表現之報告。病人一開始出現高嗜伊紅性血球症及雙下肢肥大性肺病骨關節病變,可是這些病徵在腫瘤切除後便消失。而且病人在術後十五個月持續表現良好。

並列摘要


Primary malignant fibrous histiocytoma (MFH) of the lung is a very rare pulmonary malignancy. It is often diagnosed only after other primary origin of the tumor have been excluded. Thus, the patient must be carefully evaluated for possible metastasis. There is so far no documented benefit from adjuvant chemotherapy and radiotherapy. For this reason, the favorable outcome of the patient will primarily depend on an optimal surgical resection. We report herein, for the first time, a patient presenting with a bilateral lower leg pain that turned out to be a case of MFH. We noted that the patient presented with hypereosinophilia and bilateral lower leg hypertrophic pulmonary osteoarthropathy. Subsequently, the patient underwent surgery in order to complete the removal of the tumor. After the surgical procedure, the patient recovered dramatically, and was thoroughly monitored and followed-up for 15-months, during which, the patient remained disease-free and in good condition.

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