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Fibroelastolytic Patterns of Intrinsic Skin Aging: Pseudoxanthoma Elasticum-Like Papillary Dermal Elastolysis and White Fibrous Papulosis of the Neck

內因性皮膚老化之彈力纖維分解表現:彈性假黃瘤樣乳突真皮彈力纖維分解症與頸部白色纖維丘疹症

摘要


彈性假黃瘤樣乳突真皮彈力纖維分解的特徵為許多黃白色、似彈性假黃瘤之丘疹,分布於老年人頸部及鎖骨上區域。病理特徵為乳突真皮區之彈性纖維缺失或數目減少。此病不會有家族病史,也沒有心臟血管及眼睛異常。頸部白色纖維丘疹症則好發於老年人頸部後側或雙側,臨床上為數個黃白色丘疹。我們在此報告一例彈性假黃瘤樣乳突真皮彈力纖維分解症,及另一例頸部白色纖維丘疹症。我們回顧文獻認為此兩種疾病同為內因性皮膚老化之表現。

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並列摘要


Pseudoxanthoma elasticum-like papillary dermal elastolysis is characterized by multiple whitish-yellow papules on the neck and supraclavicular regions of elderly persons. The papules resembles those in pseudoxanthoma elasticum. There is also an histological loss or decrease of the number in elastic fibers in the papillary dermis. There is no family history of such skin lesions and lack of cardiovascular or ocular abnormalities. White fibrous papulosis of the neck is characterized by several whitish to yellowish, tiny, firm papules located on the posterior or lateral sides of the neck in the elderly. We herein report a case of pseudoxanthoma elasticum-like papillary dermal elastolysis and another typical case of white fibrous papulosis of the neck. According to the literature, both diseases are best viewed as two fibroelastolytic patterns of intrinsic skin aging.

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