捐血後不適就醫之探討

Serious Adverse Events after Blood Donation and Their Related Factors

林麗玲(Li-Ling Lin) ； 劉燕珠(Yen-Chu Liu) ； 王雲龍(Yun-Lung Wang) ； 林素娟(Su-Jen Lin) ； 林國信(Kuo-Sin Lin)

《台灣醫學》 14卷4期 (2010/07) Pp. 370-376

https://doi.org/10.6320/FJM.2010.14(4).02

摘要

A serious adverse event (SAE) is defined as the occurrence of symptoms signs that are not immediately alleviated and necessitating medical care outside the blood center. It is the purpose of this study to understand the factors contributing to the adverse event and to recognize the signs and symptoms associated with those adverse reactions especially delayed adverse reactions, which is essential for the prevention of secondary harm to the donor. Retrospective analysis of adverse reactions and serious adverse events from 6 blood donation centers in Taiwan during a 5-year period (2003-2007) was done. Both Chi-square and Fisher exact test (for small sample) analysis was applied to measure the p value of the different related factors to determine if the differences between the observed data and expected data reflect a significant difference or not. A p-value of ＜0.05 is considered significant. Recorded data showed that serious adverse reactions in Taiwan Blood Donation Centers occur at the rate of about 0.02%. Vasovagal reactions accounts to about 72% of the adverse reactions and venepuncture related injury about 28%. Serious adverse reactions occur more often in female, donors below 20 years of age, and first time donors. Serious adverse events occur more often in bloodmobiles than in permanent donation sites. Blood donor education is of utmost importance in the prevention of serious adverse reactions especially those of first time, young and female blood donors. The phlebotomy skill and attitude of the staff are factors highly affecting donors' reaction during blood donation, and proper training of staff is extremely necessary, to attain a happy blood donation activity.

關鍵字

捐血後不適 ； 捐血後不適就醫 ； 迷走神經反應 ； 手臂不適症狀

並列摘要

A serious adverse event (SAE) is defined as the occurrence of symptoms signs that are not immediately alleviated and necessitating medical care outside the blood center. It is the purpose of this study to understand the factors contributing to the adverse event and to recognize the signs and symptoms associated with those adverse reactions especially delayed adverse reactions, which is essential for the prevention of secondary harm to the donor. Retrospective analysis of adverse reactions and serious adverse events from 6 blood donation centers in Taiwan during a 5-year period (2003-2007) was done. Both Chi-square and Fisher exact test (for small sample) analysis was applied to measure the p value of the different related factors to determine if the differences between the observed data and expected data reflect a significant difference or not. A p-value of ＜0.05 is considered significant. Recorded data showed that serious adverse reactions in Taiwan Blood Donation Centers occur at the rate of about 0.02%. Vasovagal reactions accounts to about 72% of the adverse reactions and venepuncture related injury about 28%. Serious adverse reactions occur more often in female, donors below 20 years of age, and first time donors. Serious adverse events occur more often in bloodmobiles than in permanent donation sites. Blood donor education is of utmost importance in the prevention of serious adverse reactions especially those of first time, young and female blood donors. The phlebotomy skill and attitude of the staff are factors highly affecting donors' reaction during blood donation, and proper training of staff is extremely necessary, to attain a happy blood donation activity.

並列關鍵字

adverse reactions ； serious adverse events ； vasovagal reactions ； venepuncture related injury