Objectives: No studies have been conducted to examine the appropriateness of ACGME’s six general competencies used to evaluate the residents in training, and to guide the curriculum of medical residency training programs in Taiwan. The objectives of this study were to examine the appropriateness of applying ACGME’s six general competencies in Taiwan, and to examine the general competencies Taiwan’s physicians should be capable of performing in their clinical practice. Methods: Criteria sampling was employed to recruit chairpersons of departments of medicine, deans of medical colleges, and vice superintendents of medical centers who are responsible for medical education. A key informant indepth interview approach was used to collect the data. Results: ACGME’s six general competencies as a guide for residency training in Taiwan were recognized as appropriate, and that differences in cultural/societal issues, and in the environment for clinical practice between Taiwan and the United States where ACGME’s six general competencies were proposed should be further considered. Conclusions: By interviewing the most influential people in medical education in Taiwan, we identified that ACGME’s six general competencies for residency training in Taiwan are appropriate, and some refi nements for them while applying to the medical encounters in Taiwan would be even better.