International Scientific Productivity on Second-Generation Antipsychotic Drugs in Taiwan: A Bibliometric Study

台灣關於第二代抗精神病劑之文章在國際性期刊的產量：一個書目計量研究

Francisco López-Muñoz ； 沈武典(Winston W. Shen) ； Raquel Moreno ； Juan D. Molina ； Concha Noriega ； Miguel A. Pérez-Nieto ； Gabriel Rubio ； Cecilio Álamo

《台灣精神醫學》 26卷2期 (2012/06) Pp. 114-129+4

https://doi.org/10.29478/TJP.201206.0008

摘要

背景：這是一個關於台灣發表與第二代（非典型）抗精神病劑的（SGAs）相關文章的書目計量學研究。方法：利用EMBASE及MEDLlNE資料庫，我們選擇了所有發表自台灣，內容描述中包括非典型*、抗精神病劑*、SGAs*、clozapine等的文章。我們使用書目計量學中，關於產量及離散性（dispersion）的指標，分別使用Price定律，及Bradford定律。我們同時也計算了不同國家的參與度指數，並將部分台灣社會及健康資料與本書目計量學的研究結果做相關性的研究。結果:我們下載了發表的359篇與SGA相關之原始文件。其中29.53%的文章與SGA臨床療效有關，40.11%的文章描述SGA的副作用。我們的研究結果符合Price定律，亦即與雙極性疾患有關的文章數呈現指數性的成長（r=0.960，線性校正後r = 0.931）。SGA最常被研究的藥物分別為clozapine（89）、risperidone（82）、aripiprazole（74）、olanzapine（62）及quetiapine（22）。利用Bradford定律的離散性分析得知，文章發表多集中在Progress in Neuro-Psychopharmacology and Biological Psychiatry期刊（56）。所有來自台灣的文章發表在90種不同期刊，而且在前10名最常發表的期刊中，有8種期刊的影響係數（impact factor）大於2。結論：台灣所發表的SGA之文章數量，在本研究的期間內呈現指數性的成長。

關鍵字

第二代抗精神病劑 ； 非典型抗精神病劑 ； 書目計量學 ； 雙極性疾患 ； 台灣

並列摘要

Background: This is a bibliometric study on the scientific papers of second generation (atypical) antipsychotic drugs (SGAs) from Taiwan. Methods: With the EMBASE and MEDLINE databases, we chose the published documents from Taiwan with the descriptors of atypical*, antipsychotic*, second-generation antipsychotic*, clozapine, risperidone, olanzapine, ziprasidone, quetiapine, sertindole, aripiprazole, paliperidone, amisulpride, zotepine, asenapine, iloperidone and lurasidone. We used bibliometric indicators of production and dispersion, i.e., Price's law on the increased scientific papers, and Bradford's law on dispersion. We also calculated the participation index of the different countries, and correlated those bibliometric data with some social and health data from Taiwan (such as total per capita expenditure on health and overall volume of production in the field of Psychiatry and Neurology). Results: We downloaded 359 SGA-related original documents published from 1993 to 2011:29.53% of them were dealt with clinical efficacy and 40.11% tolerance and safety. Our study results fulfilled Price's law, that scientific SGA papers showed exponential growth (r = 0.9601, as against an r = 0.9305 after linear adjustment). OfSGA publications, the drugs most studied are clozapine (89 papers), risperidone (82), aripiprazole (74), olanzapine (62), and quetiapine (22). Division of the results into Bradford zones yielded a nucleus published exclusively in the Progress in Neuro-Psychopharmacology and Bio logical Psychiatry (56 articles). All papers from Taiwan were published in 90 different journals, and 8 of the first 10 most often published journals for Taiwanese papers have an impact factor being greater than 2. Conclusion: The published SGA papers from Taiwan have been growing exponentially from 1933-2011, without any evidence of reaching a saturation point.

並列關鍵字

second-generation antipsychotics ； atypical antipsychotics ； bibliometry ； bipolar disorder ； Taiwan

參考文獻

Bai, YM(2012).Pharmacological studies on patients with schizophrenia in Taiwan: a compilation of literature.Taiwanese Journal of Psychiatry.26,6-18.

Bradford SC: Documentation. London: Crosby Lockwood, 1948.

Statistics Office: 2009 National Health Expenditure. Taipei: Department of Health, Executive Yuan, 2010: 27-56.

OECD Health Division: OECD Health Data 2011: Frequently Requested Data (June 30, 2011) Paris: OECD, 2011.

World Health Organization Department of Health Statistics and Informatics: World Health Statistics 2011 (May 13, 2011). Geneva: WHO, 2011.