代謝症候群與中風

Metabolic Syndrome and Stroke

許妙如(Miao-Ju Hsu) ； 廖麗君(Lih-Jiun Liaw) ； 張雅如(Ya-Ju Chang)

《物理治療》 37卷2期 (2012/06) Pp. 136-145

摘要

腦中風為國人主要死因之一，也是導致國人失能的重要病因，預防中風遂成為一個重要課題。代謝症候群集眾多個與中風風險相關的危險因子，包含血糖偏高、血壓偏高、肥胖與血脂異常等。回顧過去研究，證實代謝症候群會顯著增加初次及再次中風之風險，且中風風險隨著所具有之代謝症候群危險因子的增加而增加。因此，臨床上篩檢代謝症候群對於中風之防治有其實質意義。而中風風險之增加程度可能受到不同種族、性別所影響，但仍需要更多研究去釐清與證實。分析單一代謝症候群之危險因子與中風風險的研究方面，多數支持代謝症候群中，糖尿病前期、高血壓前期及肥胖會增加中風風險，而高密度膽固醇有降低中風風險作用，但對於總膽固醇或三酸甘油酯而言，似乎與中風風險關聯並不高。目前已知身體活動／運動對於控制代謝症候群者之血糖、血壓、血脂，以及減重，皆有裨益，也許可以幫助代謝症候群者降低中風之風險，然而目前並無相關實證，仍待未來研究去證實。

關鍵字

中風 ； 代謝症候群 ； 糖尿病 ； 高血壓 ； 肥胖

並列摘要

Stroke is one of leading causes of death as well as a major cause of adult physical disability in Taiwan. Prevention of stroke has received much attention. Metabolic syndrome has a cluster of risk factors associated with stroke, including insulin resistance, hypertension, and lipids dysfunction. Previous studies have shown that metabolic syndrome significantly increases the risks of first stroke and recurrent stroke. In addition, stroke risk increases with the number of metabolic risk factors. Hence, screening for metabolic syndrome in clinical settings is practical and important for prevention of stroke. The magnitude of stroke risk associated with metabolic syndrome might be influenced by ethnicity and gender. However, more research is needed to clarify this issue. Most studies support that prediabetes, prehypertension, and obesity increase the risk of stroke and that high density cholesterol provides a protection function for prevention of stroke. Nevertheless, total cholesterol and triglycerides seem to have weak associations with stroke risk. To date, physical activity/exercise is beneficial for metabolic syndrome to control blood glucose, blood pressure, and lipids, as well as lose weight. Physical activity/exercise may help reduce the risk of stroke. However, currently, no evidence can be found in the literature and more research is suggested to verify the conjecture.

並列關鍵字

Stroke ； Metabolic syndrome ； Diabetes ； Hypertension ； Obesity