Case Report: Immune-Mediated Polyarthritis in a Bearded Dragon (Pogona vitticeps)

病例報告：鬆獅蜥的免疫性關節炎

余品奐(Pin-Huan Yu) ； 季昭華(Chau-Hwa Chi)

《臺灣獸醫學雜誌》 36卷2期 (2010/06) Pp. 95-102

https://doi.org/10.7009/TVJ.201006.0095

摘要

病畜為一隻一歲大雌性鬆獅蜥(Pogona Vitticeps)，就診時之主訴為過去一週的四肢腫脹及關節硬化，理學檢查上，四肢均呈現痛感，尤以左前肢最為明顯。在放射線照影下則呈現四肢的軟組織腫脹，肘及膝關節關節腔擴張，無蝕骨或骨膜反應。由症狀最明顯的左前肢肘關節進行關節囊液穿刺採樣，鏡檢下，每一高倍視野下有大於10個細胞，並以炎症細胞為主，包括：10.7%滑液囊細胞，43.7%單核球，30%淋巴球及15.6%異嗜球。其中單核球呈現明顯的退行性反應及進行中的吞噬作用；而微生物的培養則均呈現陰性。再配合血液學的結果，最終診斷為多發性免疫性關節炎。此外，用於輔助哺乳類動物關節疾病診斷的TNCC及%PMN也證實於爬蟲類具有診斷價值。病畜對於免疫抑制劑量的類固醇有呈現良好的預後。

關鍵字

鬆獅蜥 ； 免疫性疾病 ； 關節炎

並列摘要

A 1-year-old captive female bearded dragon (Pogona Vitticeps) was presented with swelling of all four limbs and arthrosclerosis that had been present for one week. On physical examination, all the limbs presented with pain on palpation, especially the left forelimb. Under X-ray examination, expanded articular spaces without erosive lesions or periosteal reaction were noted in the elbow and stifle joint, together with swelling of the surrounding soft tissue. Lesions were most severe in the left elbow joint. Arthrocentesis was performed for analysis of synovial fluid and cytology. Under microscopic examination, ＞10 cells/high power field (HPF) were found, in which inflammatory cells predominated. The cells comprised 10.7% synovial cells, 43.7% monocytes, 30.0% lymphocytes and 15.6% heterophils; the monocytes showed a prominent toxic reaction, and phagocytosis was also recorded. No microorganisms or crystals were observed. All synovial fluid cultures were negative. Based on the results of hematology and cytology, immune-mediated polyarthritis was diagnosed. The total white blood cells count (TNCC) and the percentage of polymorphonuclear neutrophil leukocytes (%PMN) were obtained in an attempt to obtain a diagnosis, and the results suggest a diagnostic value for this evaluation method in reptiles. The patient was treated with prednisolone at 1.5 mg/kg orally once per day (s.i.d.) with a tapering program, which resulted in a good response.

並列關鍵字

Bearded dragon ； immune-mediated polyarthritis ； Ponoga vitticeps ； TNCC ； %PMN