透過您的圖書館登入
IP:3.146.255.127

摘要


Purpose. Amebic colitis caused by Entamoeba histolytica can range in severity from asymptomatic to life-threatening colitis. However, accurate diagnosis is difficult because of nonspecific symptoms. We aimed to evaluate diagnostic modalities and possible risk factors for amebic colitis in a case series. Methods. We reviewed patients with amebic colitis, with diagnosis proven by pathologic or serum testing, in Taipei Veterans General Hospital from January 2000 to December 2015. The symptoms, examinations, and treatment were reviewed and analyzed. Results. Eleven patients were included in this case analysis. The mean age was 51 years. The main symptoms were bloody stools, diarrhea, and abdominal pain. Nine patients underwent indirect hemagglutination assay (IHA), and all tested positive. Colonoscopy showed ulcers of variable sizes, predominantly in the rectum. Most pathology showed trophozoites with inflammation. Conclusions. Amebic colitis may present with variable nonspecific symptoms. Colonoscopy is a good diagnostic method when accompanied by biopsy for suspected amebiasis.

並列摘要


目的 阿米巴性結腸炎的表現可從無症狀,到致命的結腸炎。然而,因為非特異性症狀,精準診斷阿米巴性結腸炎是很困難的。本篇文章目的是期待藉由臺北榮民總醫院的病例回顧分析,找出阿米巴性結腸炎可能的診斷工具以及危險因子。方法 本篇文章收集台北榮民總醫院從2000 年1 月到2015 年12 月診斷出阿米巴性結腸炎的病人,並且針對症狀、檢查、以及治療進行回顧和分析。結果 共有11 例病人納入本案例研究。平均年齡為51 歲。主要症狀為便血,腹瀉,腹痛。九名患者接受了間接血凝試驗 (IHA) 的測並皆呈現陽性反應。結腸鏡檢查多以大小不一的潰瘍作呈現,且主要的部位位於直腸。大多數切片病理都有發炎反應以及阿米巴滋養體。結論 阿米巴性結腸炎可能以不同非特異性症狀呈現。如果病人症狀懷疑是阿米巴疾病,結腸鏡加上切片檢查以及間接血凝試驗將是很好的診斷方法。

參考文獻


Fleming R, Cooper CJ, Ramirez-Vega R, Huerta-Alardin A, Boman D, Zuckerman MJ. Clinical manifestations and endoscopic findings of amebic colitis in a United States-Mexico border city: a case series. Fleming et al. BMC Res Notes 2015; 8:781
Lee KC, Lu CC, Hu WH, Lin SE, Chen HH. Colonoscopic diagnosis of amebiasis: a case series and systematic review. Int J Colorectal Dis 2015; 30(1): 31-41
Centers for Disease Control, Department of Health, Taiwan. Notifiable Infectious Diseases Statistics System. Accessed 1 May 2016
Koh PS, Roslani AC, Vimal KV, Shariman M, Umasangar R, Lewellyn R. Concurrent amoebic and histoplasma colitis: a rare cause of massive lower gastrointestinal bleeding. World J Gastroenterol. 2010;16(10):1296-8.
Gupta SS, Singh O, Shukla S, Raj MK. Acute fulminant necrotizing amoebic colitis: a rare and fatal complication of amoebiasis: a case report. Cases J 2009; 2:6557.

延伸閱讀