Chronic kidney disease is great health cost burden and has made a great impact on society. The NIH Health People 2010 Report predicated that ESRD patients will double in number from year 2000 to 2010. It is a great worldwide public health burden, therefore prevention control program is mandatory. In the early kidney disease stage, education can change patient behavior and help them improve their discipline in treating the disease. The prevention strategies are: early diagnosis of kidney disease, planning for kidney disease treatment, trying to discover a reverse factor, delaying chronic kidney disease progression, preventing kidney disease complications, making the patient choose, and preparing for the dialysis mode in pre-ESRD stage.