- 期刊
Metoclopramide引起小兒錐體外徑症候群
Metoclopramide-Induced Extrapyramidal Syndromes in Children
摘要
Metoclopramide為中樞多巴胺（dopamine）接受體的拮抗劑，用於預防嘔吐、逆流性消化性食道炎、糖尿病引起之胃腸蠕動異常，長期或高劑量使用，或病患具高危險因子者，皆易產生錐體外徑症狀（Extrapyramidal syndromes，EPS），當EPS產生時應立即停藥並給予解藥緩解，本文為一位七個月及一位七歲大的小女孩因使用metoclopramide後產生不良反應之案例。
並列摘要
Metoclopramide is a CNS dopamine antagonist that is used to treat vomiting, GERD, and abnormal gastrointestinal peristalsis induced by diabetes mellitus. Long-term or high dose use of metoclopramide may easily lead to extrapyramidal syndrome (EPS), especially among those who are at high risk. If EPS occurs, physicians must halt the use of metoclopramide and then give an antidote that will relieve the symptoms. This case report describes adverse drug reactions due to metoclopramide that occurred in a seven-month old infant and in a seven-year old girl.
延伸閱讀
- Chen, P. C., & Shu, W. C. (1996). Klippel-Trenaunay-Weber症候群合併半側腦肥大：一病例報告. Acta Paediatrica Sinica, 37(2), 138-141. https://doi.org/10.7097/APS.199604.0138
- 陳啟中、薛豐曉（2012）。一位十歲男童上顎右側正中及側門齒嚴重阻生，伴隨對側下顎含齒囊腫的早期治療：病例報告。臺灣兒童牙醫學雜誌，12(2)，25-33。https://doi.org/10.6319/TJPD.2012.12(2).4
- 呂佩樺、郭松泊、彭嫈睛、何俊曄、張陽明（2013）。以巨型口腔潰瘍表現的青少年型貝歇氏病合併壞死性血管炎－病例報告。臺灣口腔顎面外科學會雜誌，24(2)，110-117。https://www.airitilibrary.com/Article/Detail?DocID=a0000494-201306-201308070008-201308070008-110-117
- 黃國軒（2007）。Analysis of Urodynamic Study in Children with Primary Monosymptomatic Nocturnal Enuresis〔碩士論文，中山醫學大學〕。華藝線上圖書館。https://doi.org/10.6834/CSMU.2007.00083
- Salido, E. J., Cabañas, V., Berenguer, M., I.Macizo, M., Candel, F. G., López, R. P., & Moraleda, J. M. (2014). Serological Findings in a Child with Paroxysmal Cold Haemoglobinuria. Case Reports in Medicine, 2014(), 255-257-056. https://doi.org/10.1155/2014/316010