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眼科民間藥用植物-皺葉萵苣之成分研究

Study on the Constituents of the Ophthalmic Folk Medicines-Lactuca sativa L. var. crispa L.

摘要


台灣產皺葉萵苣Lactuca sativa L. var. crispa L.為民間廣為食用之治療眼疾及眼睛保健蔬菜。其根部和葉部的甲醇萃取物,藉由多次管柱層析分離及純化,並用EI-MS,FAB-MS,IR。1H-NMR,13C-NMR等光譜分析技術鑑定成分的化學結構。結果分離到三個triterpenoid (taraxerol, taraxerone, β-amyrin),兩個methylbenzoate還有uracil及三個essential amino acid。其中化合物β-amyrin,據文獻報導,它能促進網膜色素上皮(RPE)細胞吞噬作用。

並列摘要


Three known triterpenoid (taraxerol, taraxerone. β-amyrin), two methylbenzoate, uracil mid three essential amino acid were isolated from Lactuca sativa L. var. crispa L. of the Ophthalmic Folk Medicines in Taiwan. Among these compounds, β-amyrin, according to literature, can enhance Retinal Pigment Epithelial (RPE) cell phagocytosis. Structure determination was carried out by spectral techniques such as, EI-MS, FAB-MS, IR, 1H-NMR arid 13C-NMR.

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