Cough, with various complex ca uses and diversity in avaible medicines, is one of the most common syndrome in clinical practice. This article proposes eight prescriptions such as Shu Zi Jiang Qi Tang, Ding Quan Tang,Ban Xia Hou Bu Tang, Ma Xing Gan Shi Tang, Xiao Qing Long Tang, Er Ker Xing Shu San, Sang Ju Yin, and Mai Men Dong Tang in clinical cough treatment to compare these medcines by the theory of treatment on the basis of Syndrome Differentiation. The content includes both the definition, causes, types, and referred descriptions of cough and the origins, compositions, treatment syndromes, and types in use of these prescriptions. After in comparison with composition, type and mechanism of above prescriptions, we can understand the difference between these prescriptions in clinical treatment. The discussions on the basis of referred cases of different types of the cough such as exogenous caugh, endogenous caugh, Mei-He Qi, asthma, and chronic bronchit s,and lead a series of discussions on the differentiation of asthma and cough in clinical treatment.