不可避免的細胞診子宮癌偽陰性抹片之案例報告

A Case of Inevitable False Negative Cytological Findings of Cervical Cancer

阮正雄(Cheng-Hsiung Roan) ； 簡陳榮(Chen-Jong Chien) ； 黃碧標(Bi-Biao Huang) ； 邱素悅(Su-Yeh Chiu) ； 曹唐義(Tang-Yi Cao)

《童綜合醫學雜誌》 6卷2期 (2012/12) Pp. 67-70

https://doi.org/10.29838/TMJ.201212.0005

摘要

子宮頸抹片（pap smear）對於子宮頸癌（uterine cervical cancer）的早期診斷有很大的幫忙。在篩檢採樣時，以採樣器自子宮頸口移行帶刷取表皮細胞，作為檢驗標的物，但在檢查時常會發生偽陰性或偽陽性的問題。在本案例中，因子宮內膜基質肉瘤突於子宮頸口，惡性腫瘤之表面覆蓋了嚴重壞死組織，因此抹片、切片都只呈現壞死組織細胞，真正惡性腫瘤細胞無法表現，而形成不可避免的偽陰性。子宮頸抹片篩檢前，婦科內診是必要的，它可提醒臨床醫師對局部異常所見應有所警覺，做進一步的診斷與治療。

關鍵字

子宮頸抹片 ； 偽陰性 ； 子宮頸癌

並列摘要

Pap smear is a useful tool for early detection of cervical cancer, although it is essential to obtain the sample from the cervical transformation zone. Here, we report a case of endometrial stromal sarcoma protruding from the endocervical canal. The tumor bulk was extensively composed of necrotic tissue, but showed a false-negative result via Pap smear microscopy and biopsy-obtained tissue analysis. In addition to Pap smear, a vaginal examination can aid in the diagnosis of cervical and uterine diseases; therefore, a thorough physical examination and further diagnostic procedures are essential to accurately detect cervical cancer.

並列關鍵字

Pap smear ； false negative ； uterine cervical cancer