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The Role of Labetalol and Propofol in the Management of HELLP Syndrome - A Case Report

Labetalol及Propofol在HELLP徵候群病患處理上之角色-病例報告

摘要


The acronym HELLP describes a syndrome of (H) hemolysis, (EL) elevated liver enzymes, and (LP) low platelets, which symptomatically defines a unique group of preeclamptic/eclamptic women. Pregnancies complicated by this syndrome are associated with poor maternal and fetal outcome. This poses a considerable challenge to the anesthesiologists as many of these patients require emergent Cesarean section. We reported a 30-year-old woman with gestation of 32 wk who sustained Cesarean section under the impression of pregnancy with HELLP syndrome. General anesthesia was performed for this patient. The preoperative evaluation, general management, and intraoperative monitoring system were described. The individual role and use of labetalol and propofol were also discussed in this report.

並列摘要


HELLP徵候群是描述一群患有子癲前症或子癲症之婦女出現溶血、肝臟酵素升高及血小板數目減少等症狀。由於此類病患可能不會出現嚴重子癲前症之臨床表現,因而常被給予錯誤之診斷。此病程進展快速,常引起母親及胎兒極高之死亡率,故常須施行剖腹產以緊急救治,對麻醉醫師造成一大挑戰。本病例報告一30歲婦女,懷孕32週出現典型HELLP徵候群之表現,被轉送至本院接受緊急剖腹產,在決定施以全身麻醉後,本文對於此類病人術前之狀況評估,麻醉前的處理,監視設備的使用詳細加以說明,並討論labetalol及propofol在此類病患於麻醉誘導時之角色及運用。

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