測試臺灣版7-12歲兒童記憶症狀評估量表之信效度

背景：化學治療是兒童癌症最主要治療方式，治癒疾病但同時也造成副作用產生。目前沒有專為癌症病童設計的症狀評估量表。研究目的：本研究目的為測試7-12歲記憶症狀評估量表(memorial symptom assessment scale, MSAS)之信效度，同時了解此量表是否適用於7-18歲之癌症病童。研究方法：本研究為橫斷式研究設計，於南臺灣兩家醫學中心小兒血液腫瘤科病房及門診收案，研究對象為滿7足歲診斷癌症之病童，同時正在接受化學治療或放射線治療；或已接受化學治療或放射線治療後兩週內者；或療程結束半年內者。量表經過前譯及後譯，並進行專家效度、內在一致性、效標效度和區辨效度的檢定。結果：共收案60人，7-12歲記憶症狀評估量表具良好的信度Cronbach’s α為.71；7-12歲記憶症狀評估量與10-18歲記憶症狀評估量表進行效標關聯效度檢測，其症狀頻率、嚴重程度及困擾程度呈現顯著性相關(r=.85，P<.001、r=.75，P<.001及r=.85，P<.001)；區辨效度檢定顯示：7-12歲記憶症狀評估量與生活品質量表呈現顯著負相關(r=-.69，P<.001)，與疲憊量表呈現顯著正相關(r=.66，P<.001)。結論與應用：7-12歲記憶症狀評估量表具有良好的信效度，同時可用於評估大於7歲癌症病童化學治療之症狀。

關鍵字

兒童癌症；症狀；量表；信效度

並列摘要

Introduction: Chemotherapy is the major treatment for pediatric cancer. It is not only cure disease but also causes high prevalence of adverse treatment-related symptoms. However, there are no symptom assessment tools designed for pediatric cancer patients. Purpose: The purpose of this study was to construct the reliability and validity of the memorial symptom assessment scale 7-12 (MSAS 7-12), and explore its suitable for pediatric cancer patients age between 7 and 18 years. Methods: The study was a cross-sectional correlational design. Participants, diagnosed with cancer undergoing chemotherapy, after chemotherapy for two weeks and off chemotherapy within six months, aged over 7 years, were recruited from two pediatric hematology units of hospitals in the south Taiwan. After forward and backward translation, the instrument was tested by content validity, internal consistency reliability, criterion-related validity, and discriminant validity. Results: Sixty pediatric cancer patients participated in this study. The MSAS 7-12 of Taiwanese version was good for internal reliability, Cronbach’s α was .71. The criterion-related validity reported that MSAS 7-12 was significantly correlated with MSAS 10-18, Pearson’s correlation coefficient was .85, .75, .85, all p<.001, respectively for symptoms frequency, severity, and disturbance. Discriminant validity reported the Pearson’s correlation was indicated that MSAS 7-12 had positive significantly correlation with Fatigue(r=-.69，P<.001)and negatively with quality of life (r=.66，P<.001). Conclusions: The MSAS 7-12 of Taiwanese version had a good reliability and validity, which can assess over 7 years pediatric cancer patients’ symptoms.