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  • 學位論文

糖尿病前期篩檢工具的建構與測試

The Development and Testing of a 6-items Pre-diabetes Screening Tool

指導教授 : 林秋菊

摘要


背景:糖尿病預防為一全世界囑目之健康議題。為確認糖尿病高危險群,健康專家以空腹血糖或飯後血糖測試做為篩檢方式,然此兩者方式並不便利。因此,欲發展一簡單糖病前期篩檢工具,不須任何抽血 數據。 目的:本研究目的為發展一簡單篩檢糖尿病前期的工具。 方法:本研究為一社區為主之糖尿病前期篩檢。受試者主要來自南台灣一社區、一區域醫院及一醫學中心體檢部。共召募1112位受試者填寫問卷及參與空腹血糖測試。測試糖尿病前期篩檢工具的敏感性、特異性及準確性。 結果:糖尿病前期篩檢工具所包括預測因為年齡、吸菸狀態、腰圍、收縮壓、高血壓疾病與心血管疾病史。此篩檢工具分數範圍4-14分,最佳切點為4分,準確性AUC為.0.72(95%CI:0.69, 0.76),敏感性、特異性、陽性預測值、陰性預測值及分別為76.89%, 54.76%, 38.23%, 及86.68%。 結論:實證資料支持本研究發展之篩檢工具為一效度及可行性高篩檢工具,可廣泛使用於社區篩檢以早期確認無症狀之糖尿病前期者。

並列摘要


Background: Diabetes prevention is a global health issues. To identify people at high risk of developing the diabetes, the healthcare professionals have to measure fasting glucose or two-hour oral glucose tolerance test (OGTT) that is inconvenient, and costly. Thus, we attempt to develop a simple prediabetes screening tool (PST) without the laboratory data. Purpose: The purpose of this study is to develop and test a simple screening tool to identify people with pre-diabetes. Methods: We conducted a consecutive community-based prediabetes survey. The subjects recruited from the community and department of physical examination of one medical center and one metropolitan hospital in southern Taiwan. The subjects (N=1112) completed the questionnaire and underwent a fasting glucose test after their regular physical examination. The area under the receiver operating characteristic curve (AUC) was used in this study to examine the sensitivity and specificity of PST . Results: Risk factors comprised in the PST include age, smoking status, waist circumference, systolic blood pressure, hypertension, and history of cardiovascular disease. Scores for the screening tool ranged between 4 and 14 points. The area under the AUC was 0.72 (95%CI:0.69, 0.76) for the cutoff point of 4, the sensitivity , specificity, positive predictive value, and negative predictive value of the screening tool was 76.89%, 54.76%, 38.23%, and 86.68%, respectively. Conclusions: Empirical data supports the PST is a valid and feasible screening tool that could be widely used to early identify prediabetes people who may be asymptomatic in the community.

並列關鍵字

prediabetes screening tool sensitivity specificity

參考文獻


行政院衛生署(2002)•國人肥胖定義及處理原則出爐 •取自http ://www.doh.gov.tw/CHT2006/DM/ SEARCH_ RESULT.aspx
行政院衛生署(2009)•建構維護全民飲食營養健康的藍圖:國民營養法•取自http://www.doh.gov.tw/CHT2006/DM/DM2_p01.aspx?class_no=25&now_fod_list_no=10400&level_no=2&doc_no=70525
行政院衛生署國民健康局(2006)•中老年保健-糖尿病•取自http://www.bhp.doh.gov.tw/BHPnet/Portal/Them_Show.
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行政院衛生署國民健康局(2006)•糖尿病防治推動現況與展望在台灣•取自

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