Hotel industry is nowadays one of the world’s fastest growing industries and has been fundamental contributors to the recovery of global economy. Human resource has become a key factor for the success of any organization, especially in hotel industry. To help shed the light about the relationship among Quality of Training, Job Satisfaction and Organizational Commitment, this study studied these factors in context of Vietnamese hotel industry. This study utilized quantitative method with full-scale survey targeted to 360 employees from 12 five-star hotels located in Hanoi, Vietnam. As a result, 301 copies of questionnaire were collected back and then the data were analyzed by SPSS, through several stages such as descriptive analysis, correlation analysis, regression analysis, independent sample t-test and One-way ANOVA analysis. This study has shown that 100% of five-star hotels in Hanoi, Vietnam have training programs and demonstrated the positive relationships among Quality of Training, Job Satisfaction and Organizational Commitment as well as the mediating effect of Job Satisfaction on the relationship between Quality of Training and Organizational Commitment. In addition, this study has shown that Male employees have higher level of job satisfaction and organizational commitment than Female. Also, employees in the range of 40-49 years old and employees who have low level of Education Background are likely to be more satisfied and committed toward organization. Based on that, this study came up with some suggestions in business, society and in research.