益生源與益生菌對慢性腎臟病病人的重要性及應用

The Importance and Application of Prebiotics and Probiotics in Patients with Chronic Kidney Disease

吳紅蓮(Hung-Lien Wu)

《腎臟與透析》 28卷2期 (2016/06) Pp. 92-96

https://doi.org/10.6340/KD.2016.28(2).10

摘要

慢性腎臟病病人蛋白質分解後在腸道經壞菌分解產生毒素如酚(phenols) 及吲哚(indoles) 的量比健康人多，這些代謝產物會加速病人心血管疾病及腎功能惡化及骨頭病變。治療慢性腎臟病病人菌叢失衡的兩大目標: 調整大腸壞菌菌叢的生長及減少細菌發酵產生代謝終產物。益生源與益生菌可以達此目標，益生源如膳食纖維、抗性澱粉及寡醣，益生菌主要有乳桿菌(lactobacillus)、鏈球菌(streptococcus)、比菲德氏菌 (bifidobacteria)。應鼓勵病人多攝取益生源，並適時使用益生菌來保護腸胃道功能及減少尿毒素。

關鍵字

益生源 ； 益生菌 ； 慢性腎臟病

並列摘要

The bacteria of intestinal produce toxins as phenols and indoles were more in patients with chronic kidney disease than healthy people, these metabolites will accelerate cardiovascular disease, deteriorate renal function and bone disease in patients. The two goals of treatment for flora imbalance in patients with chronic kidney disease: adjust the bacteria flora of the colon and reduce bacterial fermentation to produce metabolic end product. Prebiotics, such as dietary fiber, resistant starch, and oligosaccharides, and probiotics, such as lactobacillus, streptococcus, and bifidobacteria, can help to achieve those goals. It is recommended that the patients should increase the intake of prebiotics and use probiotics to protect the function of the gastrointestinal tract and reduce uremic toxins.

並列關鍵字

prebiotics ； probiotics ； chronic kidney disease