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下顎骨同時合併鱗狀細胞癌、造釉細胞瘤和含齒囊腫-病例報告

Simultaneous Squamous Cell Carcinoma, Ameloblastoma and Dentigerous Cyst in the Lower Jaw-A Case Report

摘要


從齒源性囊腫轉化成惡性腫瘤的病例很少見;造釉細胞瘤可能會從齒源性囊腫中轉變而成,鱗狀細胞癌也可能會從齒源性囊腫或造釉細胞瘤中轉化生成。但是不同來源的口腔腫瘤細胞,包括良性與惡性細胞同時出現在同一區域的病例相當罕見。排除外來或轉移性惡性腫瘤的來源是確定診斷的重要依據,對於來源細胞的診斷,需要經過病理檢查才能證實。我們報告一個病例同時有三種齒源性囊腫、造釉細胞瘤和鱗狀細胞癌病灶。病患接受下顎骨切除術和頸部淋巴廓清術,並接受胸大肌皮瓣修復缺損部位。同時在同一區域有三種病灶的病例很少,從齒源性囊腫或造釉細胞瘤轉變生成鱗狀細胞癌更是罕見,因此術前對於病患的病理診斷是很重要的,對一個大的囊腫病理檢體應做多處的顯微鏡檢查,以確定治療計劃。

並列摘要


The purpose of this report is to present a case combining of squamous cell carcinoma, ameloblastoma and dentigerous cyst. In very few instances, squamous cell carcinoma may arise from the epithelial lining of odontogenic cyst and/or ameloblastoma. It is imperative to do detail histological study to rule out the possibility of coexistence of more severe disease entity in a benign looking cystic lesion. And the treatment should be in accordance with the pathological finding to prevent undertreatment. In this report, we reviewed the literature and underswred the significance of multiple biopsies and careful pathological studies in suspicious, large cystic lesions.

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