雙側下顎骨中心性巨細胞肉芽腫術後追蹤八年－病例報告

Bilateral Mandibular Central Giant Cell Granulomas with 8-year Follow-up-A Case Report

陳佳政(Chia-Cheng Chen) ； 呂邁(Mail Lu) ； 陳韋全(Wei-Chuan Chen) ； 黃茂栓(Mao-Chuan Huang)

《臺灣口腔顎面外科學會雜誌》 23卷2期 (2012/06) Pp. 125-134

https://doi.org/10.7104/TJOMS.201206.0125

摘要

中心性巨細胞肉芽腫是一種較為罕見的巨細胞病變，致病的機轉目前仍然不明，而治療方法以手術刮除為主。本報告病例為一4歲男童，主訴為雙側臉頰有明顯腫塊，但並無合併其他症狀或系統性疾病。檢查發現雙側下顎臼齒區至骨上升支處有結實的腫塊，呈現邊緣清楚之放射線透性病灶，疑似為美童症、雙側性的造釉母細胞瘤或中心性巨細胞肉芽腫。安排全身麻醉下進行手術刮除，病理報告診斷為雙側下顎骨的中心性巨細胞肉芽腫。術後左側傷口復原良好，右側傷口則因復原進度緩慢，於第一次手術後追蹤第六年再次接受手術，術後傷口復原良好，定期追蹤至今八年，無復發狀況。

關鍵字

中心性巨細胞肉芽腫 ； 美童症 ； 改良式造袋術

並列摘要

Central giant cell granuloma is a rare giant cell disease. To date, the etiology is not clearly understood, and the main treatment strategy is surgical curettage. Our case report was a 4-year-old boy with the chief complaint of bilateral cheek swelling. He had no underlying symptom and systemic disease. In clinical examination, there were two dense tumors occupied bilateral mandibular from first molar to ascending ramus. The panoramic X-ray film revealed multilocular well-defined radiolucent lesions. According to these findings, clinical diagnosis of cherubism, ameloblastoma, and central giant cell granuloma were suspected. The boy subsequently underwent curettage of the tumors, and the pathologic report was bilateral central giant cell granulomas of mandible. The left side wound was healed well, but right side one recovered slowly, so the boy received another surgery again after 6 years. The wound of the right mandible was healed better and no sign and symptom of recurrence were noted so far.

並列關鍵字

Central giant cell granuloma ； Cherubism ； Modified marsupialization