Insulin, Lipid Profiles and Measures of Fatness in Taiwanese Women in Relation to Duration of Residence in Australia

澳洲的台灣女性胰島素、血脂質及肥胖測量與居留時間的相關性

Wan-Ping Lee ； Jennifer Lingard ； Margaret Bermingham

《Asia Pacific Journal of Clinical Nutrition》 16卷2期 (2007/06) Pp. 254-261

https://doi.org/10.6133/apjcn.2007.16.2.08

摘要

This study investigated the relationships between measures of fatness and blood insulin and lipids in Taiwanese females living in Taiwan (n=97) or Australia (n=100), and examined the effect of length of residence in Australia on these relationships. Fasting glucose and lipids were determined by Reflotron and fasting insulin using Microparticle Enzyme Immunoassay; insulin resistance (IR) was identified by HOMA. There were no significant inter-country differences in crude plasma insulin or HOMA-IR between Taiwan and Australia (51.7±42.2 vs. 45.0±29.0 pmol/L and 1.43±1.21 vs. 1.29±1.00, respectively, all p＞ 0.05), but when insulin and HOMA-IR were adjusted for waist circumference, they were greater in Taiwan (45.7±1.6 vs. 38.0±1.6 pmol/L and 1.26±1.59 vs. 1.13±1.59, respectively, all p＜ 0.05). Subjects living in Australia greater than 5 years had higher insulin and HOMA-IR values than those with less than 5 years residence (50.0±32.3 vs. 32.4±10.5 pmol/L and 1.45±1.00 vs. 0.90±0.28, respectively, all p＜ 0.01), even after adjustment for all measures of fatness. Subjects in Australia ＞ 5 years have 6 (CI, 1.3-27.9) times the risk of having insulin ＞ 50 pmol/L; the increased risk being confined to generally and/or centrally obese women. Measures of central obesity and general obesity were positively associated with HOMA-IR in both countries (r = 0.23, p＜ 0.05 and 0.27 p＜ 0.01, Taiwan, 0.43 and 0.43, both p＜ 0.01, Australia). Taiwanese females living in Australia initially appear to have a more favorable state of IR than those in Taiwan, but insulin resistance is associated with length of residence in Australia, particularly among the obese.

關鍵字

胰島素阻抗 ； 飲食 ； 肥胖 ； 血脂質 ； 台灣人 ； 澳洲的台灣移民

並列摘要

This study investigated the relationships between measures of fatness and blood insulin and lipids in Taiwanese females living in Taiwan (n=97) or Australia (n=100), and examined the effect of length of residence in Australia on these relationships. Fasting glucose and lipids were determined by Reflotron and fasting insulin using Microparticle Enzyme Immunoassay; insulin resistance (IR) was identified by HOMA. There were no significant inter-country differences in crude plasma insulin or HOMA-IR between Taiwan and Australia (51.7±42.2 vs. 45.0±29.0 pmol/L and 1.43±1.21 vs. 1.29±1.00, respectively, all p＞ 0.05), but when insulin and HOMA-IR were adjusted for waist circumference, they were greater in Taiwan (45.7±1.6 vs. 38.0±1.6 pmol/L and 1.26±1.59 vs. 1.13±1.59, respectively, all p＜ 0.05). Subjects living in Australia greater than 5 years had higher insulin and HOMA-IR values than those with less than 5 years residence (50.0±32.3 vs. 32.4±10.5 pmol/L and 1.45±1.00 vs. 0.90±0.28, respectively, all p＜ 0.01), even after adjustment for all measures of fatness. Subjects in Australia ＞ 5 years have 6 (CI, 1.3-27.9) times the risk of having insulin ＞ 50 pmol/L; the increased risk being confined to generally and/or centrally obese women. Measures of central obesity and general obesity were positively associated with HOMA-IR in both countries (r = 0.23, p＜ 0.05 and 0.27 p＜ 0.01, Taiwan, 0.43 and 0.43, both p＜ 0.01, Australia). Taiwanese females living in Australia initially appear to have a more favorable state of IR than those in Taiwan, but insulin resistance is associated with length of residence in Australia, particularly among the obese.

並列關鍵字

insulin resistance ； diet ； obesity ； blood lipids ； Taiwanese ； Taiwanese immigrants in Australia