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Epidemiologic Characteristics of Malignant Neoplasms in Taiwan: V. Nasopharyngeal Carcinoma

台灣地區惡性腫瘤之流行病學特徵:Ⅱ鼻咽癌

摘要


本研究利用台灣地區1967年至1986年之鼻咽癌死亡率與1983年至1985年間鼻咽癌發生率,以探討台灣地區近20年來鼻咽癌之年齡曲線、性別比例、地理分佈、長期變動趨勢、國際比較及移民差異等流行病學特徵。分析結果顯示台灣地區1967年至1986年間男性與女性之年齡標準化死亡率均有顯著的上升,但是男女性別比例則維持在2至3倍間沒有顯著差異。觀察近20年來各年齡層之鼻咽癌死亡率,發現自15-19歲以後死亡率急遽上升,至40-44歲時達高岑,50歲以後則呈現高原狀態。國際比較和移民研究均顯示中國人罹患鼻咽癌之危險性遠高於其他種族,但在香港、新加坡和舊金山的中國人鼻咽癌發生率卻高於台灣。由研究結果顯示鼻咽癌之發生遺傳因素佔有很重要的地位,而人生早期暴露的環境危險因子亦可能對鼻咽癌之發展有相當的作用。

關鍵字

無資料

並列摘要


Epidemiological characteristics of nasopharyngeal carcinoma were studied by examining mortality rates from 1967 to 1986 and incidence rates from 1983 to 1985. A significant increase in age-adjusted mortality rates from 1967 to 1986 was observed for both males and females, with a constant male-to-female ratio of 2:1 to 3:1. Age-specific mortality and incidence rates rose prominently from age 15-19 and peaked at age 50. Both international and migrant comparisons showed a higher risk of nasopharyngeal cancer among Chinese than among other populations. Chinese in Hong Kong, Singapore and San Francisco had significantly higher NPC incidence rates than Chinese in Taiwan. These observations suggest that genetic composition may play an important role in the determination of nasopharyngeal cancer, and that environmental risk factors which may contribute to the development of this cancer probably have their effects early in the individual's life.

並列關鍵字

nasopharyngeal neoplasms epidemiology Taiwan

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