Acute myocardial infarction (AMI) due to arthropod envenomization has rarely been reported. Herein, we report a 65-year-old woman with clinical manifestations mimicking AMI and left ventricular wall motion abnormality after honeybee sting. The patient eventually recovered from her illness with normal left ventricular wall motion on echocardiogram and T wave inversion on electrocardiogram. We also review the literatures.