- 期刊
Higher Ventricular Premature Complex Burden is Associated with Lower Systolic Blood Pressure Response
摘要
Background: Ventricular premature complexes (VPCs) with a burden higher than 10% to 20% of total daily heart beats can cause VPC-induced cardiomyopathy. The systolic blood pressure response (SBPR) is the difference between the SBP during maximal exercise and rest. A low SBPR was recently identified to be a marker of cardiomyopathy. The aim of this manuscript was to clarify the association between VPC burden and SBPR. Methods: From January to December 2015, all patients with a VPC burden larger than 240 beats/day on Holter recordings and treadmill exercise tests were enrolled. The patients with a heart rhythm other than sinus rhythm, coronary artery disease, and severe cardiomyopathy were excluded. The SBPR was measured during a treadmill test. The basic characteristics and echocardiographic findings were collected. Results: All patients were classified into three groups: Group 1; 240-1,000 VPCs/day (n = 78), Group 2; 1,000-10,000 VPCs/day (n = 54), and Group 3; ＞ 10,000 VPCs/day (n = 21). Group 1 had a higher SBPR than the other groups. Multivariate analysis revealed that only VPC burden was associated with SBPR. Receiver operating characteristic curve analysis showed that a VPC burden ＞ 1,055 beats/day predicted a SBPR＜40 mmHg. The results were consistent in all subgroups. There were no significant differences in echocardiographic findings among the groups. Conclusions: AVPC burden higher than 1,055 beats/day was associated with a reduced SBPR.
延伸閱讀
- Chen, Y. S., Chen, W. D., Chen, Y. H., Akhmerov, A., Wang, H. C., Chang, K. C., & Lin, Y. N. (2020). Atrial and Ventricular Response to Treatment of Premature Ventricular Complexes. Acta Cardiologica Sinica, 36(5), 475-482. https://doi.org/10.6515/ACS.202009_36(5).20200307A
- Lo, C. I., Lai, Y. H., Wu, J. J., Yun, C. H., Hung, C. L., Bulwer, B. E., & Yeh, H. I. (2013). Cardiac Systolic Mechanics in Heart Failure with Preserved Ejection Fraction: New Insights and Controversies. Acta Cardiologica Sinica, 29(6), 515-523. https://www.airitilibrary.com/Article/Detail?DocID=10116842-201311-201311140031-201311140031-515-523
- Chang, S. F. (2017). Interventions used to improve control of blood pressure in patients with hypertension. 健康科技期刊, 4(1), 17-20. https://doi.org/10.6979/TJHS.201707_4(1).0002
- He, M., 陳美蓉, & 林小玲 (2016). Interventions used to improve control of blood pressure in patients with hypertension. 榮總護理, 33(1), 108-110. https://doi.org/10.6142/VGHN.33.1.108
- Voon, W. C., Sheu, S. H., Hwang, Y. Y., Yen, H. W., Lee, C. S., Chang, J. S., Lin, C. C., & Lai, W. T. (1994). The Circadian Variations of Blood Pressure and Heart Rate in Patients with Mitral Valve Prolapse. The Kaohsiung Journal of Medical Sciences, 10(2), 84-88. https://doi.org/10.6452/KJMS.199402.0084