- 期刊
Non-Alcoholic Fatty Pancreas Disease is Associated with Increased Epicardial Adipose Tissue and Aortic Intima-Media Thickness
摘要
Background: We aimed to investigate whether non-alcoholic fatty pancreas disease (NAFPD) is associated with epicardial adipose tissue (EAT), which is a kind of ectopic fat accumulation, and aortic intima-media thickness (aIMT), which is associated with subclinical atherosclerosis. Methods: Fifty-four patients with NAFPD (22men; mean age: 52 ± 10 years) and 49 without NAFPD (16men; mean age: 49 ± 8 years) were included in this study. NAFPD and aIMT were evaluated using transabdominal ultrasonography (TUS). EAT was evaluated with transthoracic echocardiography. Results: EAT (6.09 ± 1.52 mm and 3.87 ± 1.31 mm, p ＜ 0.001) and aIMT [1.12 (0.60-1.90) mm vs. 0.93 (0.50-1.44) mm, p ＜ 0.001] were significantly higher in the NAFPD positive subjects, compared to the NAFPD negative subjects. Multivariate analysis showed that age (p = 0.016), body mass index (p = 0.004), and presence of NAFPD (p = 0.024) were associated with increased aIMT. In addition, multivariate analysis demonstrated that the presence of NAFPD (p ＜ 0.001) was associated with increased EAT. Conclusions: The presence of NAFPD on TUS is associated with increased aIMT and EAT. Our study results may suggest that NAFPD may reflect subclinical atherosclerosis and may be a simple warning sign for physicians.
延伸閱讀
- Schmidt, C. M., Choi, J., Powell, E. S., Yiannoutsos, C. T., Zyromski, N. J., Nakeeb, A., Pitt, H. A., Wiebke, E. A., Madura, J. A., & Lillemoe, K. D. (2009). Pancreatic Fistula Following Pancreaticoduodenectomy: Clinical Predictors and Patient Outcomes. HPB Surgery, 2009(), 54-61. https://doi.org/10.1155/2009/404520
- Wang, C. C., Lin, C. H., Chen, C. H., Wang, H. P., & Lin, J. T. (2006). Pancreaticopleural Fistula Successfully Treated by Thoracoscopic Drainage and Endoscopic Pancreatic Stenting: Report of a Case. 臺灣消化醫學雜誌, 23(2), 144-150. https://doi.org/10.6557/GJT.200606_23(2).0005
- Ullah, S., Mehmood, S., Chatha, H. A., & Mahmood, A. (2010). To Perform Thrombolysis or Not: A Case of Acute Pancreatitis Presenting with Chest Pain and Transient Left Bundle Branch Block. Case Reports in Medicine, 2010(), 114-116-027. https://doi.org/10.1155/2010/204547
- Chen, C. F., & Chiu, C. T. (2007). Clinical Experience of Intraductal Papillary Mucinous Neoplasms of the Pancreas. 臺灣消化醫學雜誌, 24(1), 1-12. https://doi.org/10.6557/GJT.200703_24(1).0001
- Chou, H. K., Chao, Y. C., Hsu, C. T., Tang, H. S., Yeh, C., Liu, Y. C., Chi, D. W., & Chiang, J. H. (1995). A Clinical Analysis of Ectopic Pancreas-Case Analysis. Journal of Medical Sciences, 16(3), 203-210. https://www.airitilibrary.com/Article/Detail?DocID=10114564-199512-201306200025-201306200025-203-210