- 期刊
Augmentation of Osteoporotic Distal Radius Fracture Fixation with an Injectable Bioresorbable Bone-Substitute Putty
並列摘要
Purpose: This study evaluated an injectable, bioresorbable, calcium-based, bioceramic bone-substitute putty for the capacity to augment osteoporotic distal radius fracture fixation. Methods: Twenty patients (12 females; mean age, 72 ± 12 years) with osteoporotic fractures of the distal radius treated between July 2006 and July 2007 were included. Fractures, which were classified as AO type A1 and A2 extra-articular and type B1 and B2 simple intra-articular, were treated with closed reduction and internal fixation involving two Kirschner wires augmented with Cem-Ostetic bone-substitute putty. Wrist range-of-motion exercises were initiated 4 weeks after K-wire fixation and 6 weeks after short arm cast fixation. Clinical symptoms and radiographic findings were evaluated every 4 weeks and analyzed using SAS version 9.1. Measurements of volar tilt, radial height, and radial inclination performed postoperatively and at the final follow-up visit were compared using the Wilcoxon signed rank test. Results: A significant difference in volar tilt (p＜0.001), but not radial length or inclination, was observed. Follow-up radiographs revealed rapid fracture healing. Bone-putty was absorbed and solid bridging callus formation was evident 3 months postoperatively. When a visual analogue scale was used to evaluate clinical symptoms, major improvements were observed on the contralateral side. Use of a Gartland and Werley scoring system revealed that 14 (70%) patients recovered function completely; results were graded as excellent. No joint arthritic changes or related complications were observed. Conclusions: Cem-Ostetic bone putty provides initial osteoconduction in osteoporotic bone. However, the extent and rate of new bone formation following augmentation depend on the fracture pattern.
延伸閱讀
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