- 期刊
- OpenAccess
Bioimpedance Phase Angle Predicts Mortality in Patients on Maintenance Hemodialysis
摘要
BACKGROUND: This study examines the associations between phase angle and dialysis mortality. METHODS: Older patients who initiate hemodialysis in Taoyuan General Hospital from January 2014 to June 2018 were enrolled. We reviewed clinical data and anthropometric measurements at the first trimester after dialysis and followed over a 4-year period. Body composition parameters were assessed 3 to 6 months after dialysis. Low, middle, and high phase angles were defined according to tertiles of phase angle in men and women. Hazard ratios (HRs) and 95% confidence interval (CI) for mortality and cumulative survival curves were evaluated by Cox hazards model and Kaplan Meier method. The discriminative power of phase angle and lean tissue index (LTI) were calculated according the area under the curve and the receiver operating characteristic curve. RESULTS: From a total of 278 hemodialysis patients, the proportion of men and women were 51.8% and 48.2%, respectively. After multivariate adjustment, phase angle was significantly associated with death in both genders (HRs [95% CI] = 0.827 [0.698-0.980] and 0.829 [0.703-0.977], Ps ＜ 0.05), whereas it was no more a predictor for death after adjusting LTI (HRs [95% CI] = 0.852 [0.725-1.002] and 0.876 [0.735-1.044], Ps ＞ 0.05). The adjusted C-statistics of phase angle and LTI to predict survival in men vs. women were 0.841 vs. 0.845 and 0.800 vs. 0.833, whereas phase angle was non-inferior to LTI in predicting death (χ^2 = 2.2925 and 0.2346, Ps ＞ 0.05). CONCLUSION: Phase angle was non-inferior to LTI in predicting dialysis death.
延伸閱讀
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