We studied Nylon / Tencel staple fiber via the ring spinning, compact spinning and MVS spinning method to discuss the yarn appearance, structure and properties. The results show that the order of yarn strength is compact spinning> ring spinning> MVS spinning. And the order of improving the hairiness index is MVS spinning> compact spinning> ring yarn spinning. The anti-pilling index of knitting fabric is 4 via MVS spinning. This study is to establish the fundamental experiment data to facilitate the subsequent development of Nylon/Tencel blended yarn.