Phsical, Behavioral, and Eelectrophysiological Comparisons of the Thermal Effects of Two CO2 Lasers

兩台二氧化碳雷射脈衝的物理、行爲，以及電生理效果之比較

楊白峰(Pai-Feng Yang) ； 嚴震東(Chen-Tung Yen)

《Acta Zoologica Taiwanica》 14卷2期 (2004/10) Pp. 77-85

https://doi.org/10.6576/AZT.2004.14.(2).2

摘要

本論文比較了TL二型及BST-18型二台二氧化碳雷射的物理及生物效果。使用熱感紙來量測雷射光圈的均勻度及大小，使用熱量計(thermopile)來測量雷射光的平均能量，並使用紅外線偵測器來測量雷射光照射黑體後的表面溫度變化。相較於TL雷射，BST雷射在相同平均能量下，光圈內熱能均勻，光束平行少有擴散現象。當雷射光照射在大鼠尾部，BST雷射需要四倍以上的平均能量才能達到與TL雷射同樣的閃尾比例。當使用相似的生物效果能量照射大腦皮層中預埋了電極的大鼠，可以測到同樣形式的誘發電位及神經細胞反應。

關鍵字

二氧化碳雷射 ； 大鼠 ； 疼痛 ； 誘發電位 ； 神經細胞活性

並列摘要

Physical and biological effects of two CO2 laser machines were compared. The two laser machines were an older one built in-house (TL #2) and a new machine (BST-18E) commercially purchased. Thermal-sensitive paper and thermosensors were used to measure the temperature profiles of the laser beam. Compared to the TL laser, the BST laser had lower maximal power, less beam divergence, and more evenly distributed thermal energy within the beam circle. The biological effects compared were the tail flick ratio, cortical evoked potential, and evoked response of ensemble cortical neurons. The TL laser (45 mJ) had an ED50 four times less than that of the BST laser (180 mJ). When comparable laser energy levels were used, similar patterns of evoked cortical field potentials and ensemble neuronal responses composed of short- and long-latency components were seen in the primary somatosensory cortex of the rat.

並列關鍵字

CO2 laser ； cortical field potential ； ensemble unit activity ； pain ； rat ； temperature change