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修正簡易營養評估量表(MNA)以改善其評估血液透析患者營養風險之效能

Modifying the Short-form Mini-Nutritional Assessment to Improve the Prediction of Nutritional Risk in Patients on Hemodialysis

摘要


目標:改良MNA(Mini-Nutritional Assessment)使其更適用於血液透析(hemodialysis, HD)患者的營養評估。方法:本研究徵求中部某地區醫院門診洗腎中心血液透析患者100名(18-97歲,男43女57名)。經同意後,以短式及長式MNA-台灣二版評估營養狀況並與生化指標比較。MNA台灣二版為採用台灣老人體位指標的改良版。版本之修正以選擇較能反應HD病情的非短式題項(如O題)與較不反應HD病情的短式題項(如E題)互換題位,並檢定其改良成效。以Wilcoxon Signed-Rank Test進行事後檢定,比較短式MNA台灣二版各改良版本與長式MNA台灣二版的評估結果。以Pearson's相關分析長式及各短式MNA台灣二版的總分與血清白蛋白、血清肌酸酐、住院天數、及急診次數的相關性。結果:本研究發現短式MNA台灣二版用於評估血液透析病患時,以量表O題(自評營養狀況)取代(對換)E題(失智),最能改進評估功能,且其評估成果與長式MNA台灣二版相當一致。結論:本研究的結果顯示MNA量表以O題(自評營養狀況)取代(對換)E題(失智)或D題(精神壓力)最能改進其血液透析患者的評估功能。此簡單的改良,使短式MNA量表可適用於台灣的血液透析患者。

並列摘要


Objectives: To modify the Mini-Nutritional Assessment (MNA) so that it would be suitable for use in hemodialysis (HD) patients. Methods: Subjects were 100 HD outpatients (18-97 years of age, 43 men and 57 women) recruited from a district hospital in Central Taiwan. With their consent, we rated the nutritional status of each subject with the long-, short-, and modified short-form versions of the MNA and measured their biochemical values. We examined various alternative short-form versions of the MNA based on the dietary characteristics of HD patients. The study used the Wilcoxon Signed-Rank Test, Pearson's correlation analysis and the crosstabulation test to evaluate the ability of the short-form versions to predict the long-form MNA (T2). Results: Results showed that a modified short-form version that exchanged item O (selfrated nutritional status) for item E (dementia) improved the predictive ability of the MNA in HD patients. The modified short-form performed well compared to the long-form. Conclusions: The study demonstrated that replacing item O for E or D in the MNA can best improve the functionality of the MNA. This simple revision makes the short-form suitable for assessing the risk of malnutrition in patients on hemodialysis.

參考文獻


台灣腎臟醫學會:台灣血液透析診療指引 (2004/12/30)。http://www.tsn.org.tw/UI/F/F005.aspx。引用2011/06/01。Taiwan Society of Nephrology. Clinical guidelines for hemodialysis in Taiwan (December 30, 2004). Available at: http://www.tsn.org.tw/UI/F/F005.aspx. Accessed June 1, 2011. [In Chinese]
Barone, L.,Milosaljevic, M.,Gazibarich, B.(2003).Assessing the older person: is the MNA a more appropriate nutritional assessment tool than the SGA?.J Nutr Health Aging.7,13-7.
Cooper, B. A.,Bartlett, H.,Aslani, A.,Aallen, B. J.,Ibels, L. S.,Pollock, C. A.(2002).Validity of subjective global assessment as a nutritional marker in end-stage renal disease.Am J Kidney Dis.40,126-32.
Cooper, B. A.,Penne, E. L.,Bartlett, L. H.,Pollock, C. A.(2004).Protein malnutrition and hypoalbuminemia as predictors of vascular events and mortality in ESRD.Am J Kidney Dis.43,61-6.
de Castro, M. C.,de Oliveira, F. C.,da Silveira, A. C.(2010).Importance of the monthly biochemical evuluation to identify patients on hemodialysis with malnutrition.J Bras Nefrol.32,349-54.

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