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Surgery of Triple Synchronous Lung Cancer with Different Cell Types as Demonstrated by (18)^F-FDG PET Imaging

多重原發性肺癌在不同強度正子攝影顯影下之手術治療-個案報告

摘要


臨床上是否為轉移性肺腫瘤或均為原發性肺癌,因缺乏基因學上之分子標記,常造成診斷及治療上之困擾。70歲女性,臨床表徵為持續咳嗽及漸進性喘,時間達一個月之久。經詳細檢查,正子攝影顯示左主支氣管及左肺上葉有腫塊顯影,左肺下葉有一1.4公分腫塊無顯影。支氣管鏡檢證實左主支氣管為鱗狀上皮細胞癌,左肺上葉及下葉腫瘤術後病理組織依新肺腺癌分類準則,分別為微侵犯性肺腺癌及侵犯性肺腺癌,然而術前的正子攝影呈高度顯影的左肺上葉腫塊,術後為微侵犯性肺腺癌;相反地,術前無正子攝影的左肺下葉腫塊,術後為侵犯性肺腺癌。

並列摘要


Synchronous multiple primary lung cancer (MPLC) is presumed to be an uncommon entity. In the absence of easily available genetic or molecular markers, the differentiation between MPLC and isolated pulmonary metastasis will remain difficult in a clinical setting, leading to controversies regarding management considerations. We present a rare case of synchronous MPLC with differences in (18)^F-FDG avidity on positron emission tomography-computed tomography imaging. We also share our experience with its diagnosis, management, and histopathological results.

並列關鍵字

lung cancer synchronous PET/CT surgery histology

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