- 期刊
POSTOPERATIVE RADIOTHERAPY FOR CARCINOSARCOMA ARISING FROM PAROTID MIXED TUMOR : A CASE REPORT AND REVIEW OF THE LITERATURE
耳下腺癌肉瘤接受手術後放射治療：病例報告與文獻回顧
摘要
Carcinosarcoma, a true malignant mixed tumor, is rarely seen in the parotid glands. The majority of cases arise from existing benign mixed tumors. Carcinosarcoma is considered an aggressive malignancy with a high probability of local recurrence and distant metastases. We report a case of carcinosarcoma arising from a parotid mixed tumor (pleomorphic adenoma) in a 56-year-old female. Initially, the disease presented as a progressively enlarged mass with local tenderness in the left parotid gland. Clinically, there were no symptoms or signs of facial nerve palsy. Contrast-enhanced computed tomography (CT) performed at a different hospital revealed a tumor (4.1 × 3 × 2.5 cm) in the left parotid gland without any enlarged cervical lymphadenopathies. Subsequently, the patient underwent a left total parotidectomy with full preservation of the left facial nerve. The pathology report revealed carcinosarcoma arising from the mixed tumor. After surgery, the patient received adjuvant radiotherapy (66 Gy/33 fractions). She was regularly followed up at our outpatient clinic with routine physical examinations and imaging studies. The patient remained alive with no evidence of disease during the 65-month follow up.
並列摘要
耳下腺癌肉瘤是相當罕見的唾液腺惡性腫瘤，大多數病例均源自於先前存在的良性唾液腺混合瘤。癌肉瘤因為具有很高的局部復發與遠端轉移機率，因此被視為高惡性度之惡性腫瘤。此病例報告為56 歲女性因先前耳下腺多型性腺瘤轉化為耳下腺癌肉瘤。患者首先呈現左側耳下腺快速長大之壓痛性腫塊，但無顏面神經麻痺之症狀與徵候。於外院頭頸部電腦斷層顯示左側耳下腺腫塊但無頸部淋巴腫大。此病患於本院接受左側耳下腺切除術並保留顏面神經功能。病理報告證實為源自耳下腺多型性腺瘤之癌肉瘤。病患後續接受手術後放射治療（66 戈雷）及定期門診追蹤檢查。經過65 個月門診追蹤此病患仍呈現無病存活。
延伸閱讀
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