Mycorrhizal fungi are one of the fungi that are ubiquitous in soil that can be form a symbiotic relationship with plants and therefore, play an important role in the natural ecosystem. When mycorrhizal fungi associated with plant roots, the plant appearance and physiology would change. The root exudates of the mycorrhizae affect the soil physicochemical properties and influence microbial community structure. Interaction between mycorrhizal fungi and specific soil bacteria can directly or indirectly enhance plant growth, and affect the rhizosphere bacterial community structure. These beneficial rhizosphere soil bacteria also involved in the main cycles of mineral nutrients in the nature, and help maintain the function and stability of the ecosystem. Currently, the research on the interaction between mycorrhizal and rhizosphere microorganisms is still in the exploration stage, microbial ecologists can further understand the interaction with the development of advance molecular technologies.