This article discusses the challenges that an individual experiences in the face of death. It points out that people as subjects play an integrative role to feeling and experience the unknown and uncertainty of the death. Each of us experiences death anxiety when we are on the verge of death, and we may avoid or deny this situation as one of the coping strategies. By presenting a terminal case who accepted the hospice and palliative care, we discussed the critical issues of adapted process to death. Finally, we proposed suggestions on how the clinical workers could support patients' death preparation and assist the patients to be more responsible for their own death.